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犬咬伤继发急性胆囊炎

Acute cholecystitis secondary to dog bite.

作者信息

Elliott James, Donaldson Eric

机构信息

Department of General Surgery, Toowoomba Hospital, 154 Pechey Street, South Toowoomba, Queensland, Australia.

出版信息

Int J Surg Case Rep. 2019;55:230-232. doi: 10.1016/j.ijscr.2019.02.012. Epub 2019 Feb 12.

Abstract

INTRODUCTION

The gram-negative bacteria known as Capnocytophaga canimorsus (C. canimorsus) is found in dog saliva and rarely can cause severe infection in humans following a bite or scratch. There has previously been just a single case described in the literature of Acute Acalculous Cholecystitis (AAC) secondary to C. canimorsus.

PRESENTATION OF CASE

Here we describe the second ever published case of C. canimorsus bacteremia presenting with acute cholecystitis. The patient presented with epigastric pain and sepsis three weeks post domestic dog bite. On further examination, he was Murphy's sign positive. Investigations included blood cultures, Ultrasound Scan and Computed Tomography of the Abdomen. He was treated with intravenous fluid resuscitation, and intravenous ceftriaxone and metronidazole. He required an extended course of antibiotics for complete symptom resolution. His blood cultures were positive for C. Canimorsus.

DISCUSSION

This case highlights the ever-present need for thorough history and examination, and consideration of prolonged antibiotics for cases of cholecystitis that could be secondary to C. canimorsus bacteremia.

CONCLUSION

We strongly advocate blood cultures in patients who present with abdominal pain and sepsis, particularly when they have a recent history of animal bite. In cases of cholecystitis secondary to C. canimorsus it may be necessary to monitor the patient's progress more closely and treat with prolonged targeted antibiotic therapy.

摘要

引言

革兰氏阴性菌犬咬二氧化碳嗜纤维菌(C. canimorsus)存在于犬类唾液中,在人类被咬伤或抓伤后极少会引发严重感染。此前文献中仅描述过一例由犬咬二氧化碳嗜纤维菌引起的急性非结石性胆囊炎(AAC)。

病例介绍

在此我们描述第二例已发表的以急性胆囊炎为表现的犬咬二氧化碳嗜纤维菌血症病例。患者在被家犬咬伤三周后出现上腹部疼痛和败血症。进一步检查时,墨菲氏征阳性。检查包括血培养、腹部超声扫描和计算机断层扫描。给予患者静脉补液复苏,并静脉注射头孢曲松和甲硝唑。为使症状完全缓解,他需要延长抗生素疗程。其血培养结果显示犬咬二氧化碳嗜纤维菌呈阳性。

讨论

该病例凸显了始终需要全面了解病史并进行检查,以及对于可能继发于犬咬二氧化碳嗜纤维菌血症的胆囊炎病例考虑延长使用抗生素的必要性。

结论

我们强烈主张对出现腹痛和败血症的患者进行血培养,尤其是近期有动物咬伤史的患者。对于继发于犬咬二氧化碳嗜纤维菌的胆囊炎病例,可能有必要更密切地监测患者病情进展,并采用延长疗程的针对性抗生素治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdb1/6378841/a50eb9dade3f/gr1.jpg

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