University of Nebraska Medical Center/Children's Hospital and Medical Center, 8200 Dodge Street, Omaha, NE 68114, USA.
J Pediatr Urol. 2019 May;15(3):256.e1-256.e5. doi: 10.1016/j.jpurol.2019.01.004. Epub 2019 Jan 23.
Some infants with obstructed megaureters or ectopic ureters requiring surgery undergo a cutaneous ureterostomy followed by definitive repair after 12 months of age. Since 2013, a 'mini' extravesical reimplant with or without 'mini' tapering (MER) was performed instead of cutaneous ureterostomy in such infants.
To describe the technique and outcomes for MER.
This is a retrospective review of infants younger than 6 months who underwent MER. MER consists of a 2- to 3-cm extravesical tunnel, regardless of the ureter diameter. 'Mini' tapering consisted of an adventitial sparing technique involving only the distal 2-3 cm of the ureter. Details of the technique are included in the video. The main outcomes were postoperative symptomatic urinary tract infections (UTI's) and reoperations. Voiding function was assessed at the last contact with the family.
Nine consecutive infants underwent MER from July 2013 to March 2018. Four patients had ectopic ureters and five had primary obstructed megaureters. The median ureteral diameter was 1.5 cm. Indications for surgery were as per the British Association of Pediatric Urologists guidelines on megaureters. All patients had 3-month postoperative renal ultrasound, and seven of the nine patients had postoperative voiding cystourethrogram (VCUG). One patient with a normal postoperative VCUG and MAG 3, as well as resolved hydroureteronephrosis had a few postoperative febrile UTIs but no more for >1 year at the last follow-up. At a median time from surgery of 44 months, there have been no reoperations (except cystoscopy with stent removal). With regard to voiding function, six patients were successfully potty trained, one has bowel and bladder incontinence at the age of 4 years - with stable renal ulstraound -, and two are younger than 2 years.
MER has been the only surgery needed for the cohort of nine infants younger than 6 months with distal ureteral obstruction at a median time from surgery of 44 months. Voiding function does not appear to be affected by the operation.
For babies younger than 6 months of age in need of surgery for obstructed distal ureter, MER appears to be a feasible and effective option, associated with reduced morbidity and reoperation rate compared to the alternatives.
一些患有巨输尿管梗阻或异位输尿管的婴儿需要手术,他们在 12 个月大后接受皮输尿管造口术,然后再进行确定性修复。自 2013 年以来,对于此类婴儿,我们采用了一种“迷你”的经膀胱外再植术,无论输尿管直径如何,均无需进行皮输尿管造口术。
描述 MER 的技术和结果。
这是一项回顾性研究,纳入了年龄小于 6 个月的接受 MER 的婴儿。MER 包括一个 2-3cm 的膀胱外隧道,无论输尿管直径如何。“迷你”输尿管再植术采用的是一种仅涉及输尿管远端 2-3cm 的外膜保留技术。该技术的详细信息包含在视频中。主要结局是术后症状性尿路感染(UTI)和再次手术。最后一次与患儿家属接触时评估排尿功能。
2013 年 7 月至 2018 年 3 月期间,连续 9 例婴儿接受了 MER。4 例患儿患有异位输尿管,5 例患儿患有原发性巨输尿管梗阻。输尿管的平均直径为 1.5cm。手术指征均符合英国小儿泌尿科医师协会(British Association of Pediatric Urologists)的巨输尿管指南。所有患儿均在术后 3 个月接受了肾脏超声检查,9 例患儿中有 7 例接受了术后排尿性膀胱尿道造影术(voiding cystourethrogram,VCUG)。1 例术后 VCUG 和 MAG3 正常,且肾盂积水消退的患儿仅发生过几次术后发热性 UTI,但在最后一次随访时已超过 1 年未再发生。在平均 44 个月的手术时间后,无再次手术(除了因留置支架而进行的膀胱镜检查)。就排尿功能而言,6 例患儿成功进行了大小便训练,1 例 4 岁时出现肠膀胱失禁(但肾脏超声稳定),2 例患儿年龄小于 2 岁。
对于平均手术时间为 44 个月的 9 例小于 6 个月的远端输尿管梗阻婴儿,MER 是唯一需要的手术。手术似乎不影响排尿功能。
对于需要手术治疗远端输尿管梗阻的 6 个月以下婴儿,MER 似乎是一种可行且有效的选择,与替代方案相比,其发病率和再次手术率更低。