Department of Ophthalmology, Christian Medical College, Vellore, Tamil Nadu, India.
Indian J Ophthalmol. 2019 Mar;67(3):433-435. doi: 10.4103/ijo.IJO_925_18.
A 25-year-old man presented with decreased vision in the left eye with hypopigmented elevated subretinal lesion over the optic disk with abnormal vasculature, subretinal and retinal hemorrhages, and fluid in the macula. An area of high spike over the disk with corresponding orbital shadowing was seen on B scan ultrasonography. Fundus fluorescein angiography revealed abnormal vasculature. Systemic examination revealed facial angiofibroma, ashleaf spot, and dental pits with multiple cortical tubers on CT brain. Intravitreal injection of bevacizumab led to visual and tomographic improvement. Abnormal retinal vascularization and exudation in young individuals may be a presenting feature in tuberous sclerosis.
一位 25 岁男性，左眼视力下降，视盘上方有色素减退性隆起性脉络膜视网膜下病变，伴有脉络膜视网膜出血和黄斑区积液。B 型超声显示视盘上方有一高尖波，伴有眶内阴影。眼底荧光血管造影显示异常血管。全身检查发现面部血管纤维瘤、Ashleaf 斑和牙釉质凹陷，以及 CT 脑皮质多发结节。玻璃体内注射贝伐单抗后视力和断层扫描均有改善。青少年出现异常视网膜血管化和渗出可能是结节性硬化症的表现特征。
