Departamento de Diagnóstico Laboratorial, Instituto Português de Oncologia de Lisboa, Francisco Gentil, Rua Prof. Lima Basto, Lisbon, Portugal.
Department of Anatomic Pathology, Hospital Clinic, University of Barcelona, Barcelona, Spain.
Virchows Arch. 2019 Jun;474(6):649-665. doi: 10.1007/s00428-019-02543-7. Epub 2019 Feb 18.
The field of haematopathology is rapidly evolving and for the non-specialized pathologist receiving a specimen with the possibility of a lymphoid malignancy may be a daunting experience. The coincidence of the publication, in 2017, of the WHO monographies on head and neck and haematopoietic and lymphoid tumours prompted us to write this review. Although not substantially different from lymphomas elsewhere, lymphomas presenting in this region pose some specific problems and these are central to the review. In addition, differences in subtype frequency and morphological variations within the same entity are discussed. The difficulty in diagnosis related to some specimens led us to briefly mention common subtypes of systemic lymphomas presenting in the head and neck region.
血液病理学领域正在迅速发展,对于非专业病理学家来说,收到可能患有淋巴恶性肿瘤的标本可能是一种令人生畏的体验。2017 年,世卫组织关于头颈部和造血及淋巴组织肿瘤的专着的出版正好促成了这篇综述的撰写。尽管与其他部位的淋巴瘤并无实质性差异,但出现在该区域的淋巴瘤确实存在一些特殊问题,这些问题是综述的核心。此外,还讨论了同一实体中亚型频率和形态变化的差异。一些标本的诊断难度促使我们简要提及了头颈部常见的全身性淋巴瘤的常见亚型。