Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, MS E-46, Atlanta, GA, 30333, USA.
AIDS Behav. 2019 Dec;23(12):3277-3285. doi: 10.1007/s10461-019-02420-z.
We evaluated characteristics associated with recent HIV infection among persons who inject drugs (PWID) from 19 U.S. cities who participated in 2012 National HIV Behavioral Surveillance. Recent infection was defined as having a reactive HIV test, a Bio-Rad Avidity index cutoff ≤ 30%, no reported HIV diagnosis ≥ 12 months before interview, and no evidence of viral suppression. Of 8667 PWID, 50 (0.6%) were recently HIV infected. Having a greater number of sex partners (≥ 2 partners vs. 0) [prevalence ratio (PR) 4.7, 95% confidence interval (CI) 1.3-17.8], injecting heroin and other drugs (PR 3.0, 95% CI 1.3-6.6) or exclusively non-heroin drugs (PR 5.9, 95% CI 1.7-20.7) compared to injecting only heroin, and having male-male sex in the past year (PR 7.1, 95% CI 3.0-16.6) were associated with recent infection. Promoting not only safe injection practices but also safe sex practices will be key to preventing new HIV infections.
我们评估了来自 19 个美国城市的注射毒品者（PWID）中与近期 HIV 感染相关的特征，他们参加了 2012 年全国 HIV 行为监测。近期感染定义为 HIV 检测呈阳性反应，Bio-Rad 亲合力指数截断值≤30%，在访谈前 12 个月无 HIV 诊断报告，且无病毒抑制证据。在 8667 名 PWID 中，有 50 人（0.6%）最近感染了 HIV。性伴侣数量较多（≥2 个与 0 个相比）[流行比（PR）4.7，95%置信区间（CI）1.3-17.8]，与仅注射海洛因相比，注射海洛因和其他药物（PR 3.0，95%CI 1.3-6.6）或仅注射非海洛因药物（PR 5.9，95%CI 1.7-20.7），以及在过去一年中有男性间性行为（PR 7.1，95%CI 3.0-16.6）与近期感染相关。促进安全注射和性行为实践将是预防新的 HIV 感染的关键。
