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Shared mechanisms: osteoporosis and Alzheimer's disease?

作者信息

Dengler-Crish Christine M, Elefteriou Florent

机构信息

Department of Pharmaceutical Sciences, Northeast Ohio Medical University, Rootstown, OH 44272, USA.

Department of Orthopedics, Baylor College of Medicine, Houston, TX 77030, USA.

出版信息

Aging (Albany NY). 2019 Feb 19;11(5):1317-1318. doi: 10.18632/aging.101828.

DOI:10.18632/aging.101828
PMID:30779704
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6428104/
Abstract
摘要

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本文引用的文献

1
Evidence of Wnt/β-catenin alterations in brain and bone of a tauopathy mouse model of Alzheimer's disease.阿尔茨海默病tau 病模型脑和骨中 Wnt/β-连环蛋白改变的证据。
Neurobiol Aging. 2018 Jul;67:148-158. doi: 10.1016/j.neurobiolaging.2018.03.021. Epub 2018 Mar 23.
2
Early Evidence of Low Bone Density and Decreased Serotonergic Synthesis in the Dorsal Raphe of a Tauopathy Model of Alzheimer's Disease.阿尔茨海默病tau蛋白病模型中骨密度降低和中缝背核5-羟色胺能合成减少的早期证据。
J Alzheimers Dis. 2017;55(4):1605-1619. doi: 10.3233/JAD-160658.
3
Bone loss and osteoporosis are associated with conversion from mild cognitive impairment to Alzheimer's disease.骨质流失和骨质疏松与从轻度认知障碍转变为阿尔茨海默病有关。
Curr Alzheimer Res. 2014;11(7):706-13. doi: 10.2174/1567205011666140812115818.
4
Wnt signaling in the nervous system and in Alzheimer's disease.Wnt 信号在神经系统和阿尔茨海默病中的作用。
J Mol Cell Biol. 2014 Feb;6(1):64-74. doi: 10.1093/jmcb/mjt051.
5
Swedish mutant APP suppresses osteoblast differentiation and causes osteoporotic deficit, which are ameliorated by N-acetyl-L-cysteine.瑞典突变 APP 抑制成骨细胞分化并导致骨质疏松症缺陷，而 N-乙酰-L-半胱氨酸可改善这一状况。
J Bone Miner Res. 2013 Oct;28(10):2122-35. doi: 10.1002/jbmr.1954.
6
The relation between hip fracture and alzheimer's disease in the canadian national population health survey health institutions data, 1994-1995. A cross-sectional study.1994 - 1995年加拿大国家人口健康调查健康机构数据中髋部骨折与阿尔茨海默病的关系。一项横断面研究。
Ann Epidemiol. 2000 Oct 1;10(7):461. doi: 10.1016/s1047-2797(00)00085-5.
7
Hip fracture.髋部骨折
Clin Geriatr Med. 1994 Nov;10(4):589-609.