Department of Emergency Medicine, University of Pennsylvania School of Medicine, 3400 Spruce Street, Philadelphia, PA 19104, USA; Center for Resuscitation Science, University of Pennsylvania School of Medicine, University of Pennsylvania Blockley Hall, 423 Guardian Drive, Room 414A, Philadelphia, PA 19104, USA.
Department of Emergency Medicine, University of Pennsylvania School of Medicine, 3400 Spruce Street, Philadelphia, PA 19104, USA.
Resuscitation. 2019 Apr;137:140-147. doi: 10.1016/j.resuscitation.2019.02.013. Epub 2019 Feb 16.
Transesophageal echocardiography (TEE) has been proposed as a modality to assess patients in the setting of cardiac arrest, both during resuscitation care and following return of spontaneous circulation (ROSC). In this study we aimed to assess the feasibility and clinical impact of TEE during the emergency department (ED) evaluation during out-of-hospital cardiac arrest (OHCA).
We conducted a prospective observational study consisting of a convenience sample of adult patients presenting to the ED of an urban university medical center with non-traumatic OHCA. TEE was performed by emergency physicians following intubation. Images and clinical data were analyzed. TEE was used intra-arrest in order to assist in diagnosis, assess cardiac activity and determine CPR quality by assessing area of maximal compression (AMC), using a 4 view protocol.
A total of 33 OHCA patients were enrolled over a one-year period, 21 patients (64%) presented with ongoing CPR and 12 (36%) presented with ROSC. The 4-view protocol was completed in 100% of the cases, with an average time from ED arrival to TEE of 12 min (min 3 max 30 SD 8.16). Fine ventricular fibrillation (VF) was recognized in 4 (12%) cases thought to be in asystole, leading to defibrillation, and 2 cases of pseudo-PEA were identified. Right ventricular (RV) dilation, was seen in 12 (57%) intraarrest cases. Intra-cardiac thrombus was found in one case, leading to thrombolysis. The AMC was identified over the aortic root or LVOT in 53% of cases. TEE was found to have diagnostic, therapeutic or prognostic clinical impact in 32 of the 33 cases (97%).
TEE is feasible and clinically impactful during OHCA management. Resuscitative TEE may allow for characterization of cardiac activity, including identification of pseudo-PEA and fine VF, determination of reversible pathology, and optimization of CPR quality.
经食管超声心动图(TEE)已被提议用于评估心脏骤停患者,包括在复苏护理期间和自主循环恢复(ROSC)后。在这项研究中,我们旨在评估 TEE 在院外心脏骤停(OHCA)的急诊科(ED)评估中的可行性和临床影响。
我们进行了一项前瞻性观察研究,纳入了来自城市大学医学中心 ED 的非创伤性 OHCA 成年患者的便利样本。TEE 由急诊医师在插管后进行。分析图像和临床数据。TEE 在心脏骤停期间使用,目的是协助诊断、评估心脏活动,并通过评估最大压缩面积(AMC)来确定 CPR 质量,使用 4 视图方案。
在一年的时间里共纳入了 33 例 OHCA 患者,21 例(64%)患者在进行持续 CPR,12 例(36%)患者 ROSC。在所有病例中均完成了 4 视图方案,从 ED 到达到 TEE 的平均时间为 12 分钟(min 3 max 30 SD 8.16)。在被认为是停搏的 4 例(12%)病例中识别出细微室颤(VF),导致除颤,并且识别出 2 例假性 PEA。在 12 例(57%)心脏骤停病例中观察到右心室(RV)扩张。在 1 例中发现心内血栓,导致溶栓。在 53%的病例中,在主动脉根部或 LVOT 识别到 AMC。TEE 在 33 例中的 32 例(97%)中具有诊断、治疗或预后的临床影响。
TEE 在 OHCA 管理中是可行的,具有临床意义。复苏性 TEE 可以对心脏活动进行特征描述,包括识别假性 PEA 和细微 VF、确定可逆性病理,并优化 CPR 质量。