Aoki Y, Yoshinaga E, Tamazawa O
Nihon Shishubyo Gakkai Kaishi. 1988 Dec;30(4):996-1007. doi: 10.2329/perio.30.996.
The purpose of this study was to determine the protein patterns in gingival crevicular fluid relation to the isoelectric focusing protein patterns of GCF and to clinical evaluations. GCF was collected with filter paper from 105 subjects. The probing depth, the gingival index (Löe & Silness) and the plaque index (Silness & Löe) as clinical evaluations The results follow: 1. The main isoelectric focusing protein patterns of GCF were between pH 5.5 and 7.5. In comparison, the GCF and the serum from the same patients showed patterns to similar serum albumin. 2. Between of GCF pH 5.5 and 7.5 the protein patterns that ranged over 60% was pI 5.65, 6.45, 6.55, 6.75 and 7.00. The frequencies of the ranges of protein patterns and clinical evaluation were compared by the X2 test. pI 5.65, 6.45, 6.55 and 6.75 and PD were significant different, as were pI 6.45, 6.55 and 6.75 and GI. But each pI and PIl. were not significantly different.
本研究的目的是确定龈沟液中的蛋白质模式与龈沟液等电聚焦蛋白质模式以及临床评估之间的关系。用滤纸从105名受试者中收集龈沟液。探测深度、牙龈指数（Löe & Silness）和菌斑指数（Silness & Löe）作为临床评估指标。结果如下：1. 龈沟液的主要等电聚焦蛋白质模式在pH 5.5至7.5之间。相比之下，同一患者的龈沟液和血清显示出与血清白蛋白相似的模式。2. 在龈沟液pH 5.5至7.5之间，占比超过60%的蛋白质模式的等电点为5.65、6.45、6.55、6.75和7.00。通过X2检验比较蛋白质模式范围的频率与临床评估结果。等电点5.65、6.45、6.55和6.75与探测深度有显著差异，等电点6.45、6.55和6.75与牙龈指数也有显著差异。但各等电点与菌斑指数之间无显著差异。
