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按种族划分的产后再入院产妇结局。

Maternal outcomes by race during postpartum readmissions.

机构信息

Department of Obstetrics and Gynecology, College of Physicians and Surgeons, Columbia University, New York, NY.

Department of Obstetrics and Gynecology, College of Physicians and Surgeons, Columbia University, New York, NY.

出版信息

Am J Obstet Gynecol. 2019 May;220(5):484.e1-484.e10. doi: 10.1016/j.ajog.2019.02.016. Epub 2019 Feb 17.

Abstract

BACKGROUND

Maternal race may be an important risk factor for postpartum readmissions and associated adverse outcomes.

OBJECTIVE

To determine the association of race with serious complications during postpartum readmissions.

STUDY DESIGN

This repeated cross-sectional analysis used the National (Nationwide) Inpatient Sample from the Healthcare Cost and Utilization Project from 2012 to 2014. Women ages 15-54 readmitted postpartum after a delivery hospitalization were identified by Centers for Disease Control and Prevention criteria. Race and ethnicity were characterized as non-Hispanic white, non-Hispanic black, Hispanic, Asian or Pacific islander, Native American, other, and unknown. Overall risk for readmission by race was determined. Risk for severe maternal morbidity during readmissions by race was analyzed. Individual outcomes including pulmonary edema/acute heart failure and stroke also were analyzed by race. Log-linear regression models including demographics, hospital factors, and comorbid risk were used to analyze risk for severe maternal morbidity during postpartum readmissions.

RESULTS

Of 11.3 million births, 207,730 (1.8%) women admitted postpartum from 2012 to 2014 were analyzed, including 96,670 white, 47,015 black, and 33,410 Hispanic women. Compared with non-Hispanic white women, non-Hispanic black women were at 80% greater risk of postpartum readmission (95% confidence interval, 79%-82%) whereas Hispanic women were at 11% lower risk of readmission (95% confidence interval, 10%-12%). In unadjusted analysis, compared with non-Hispanic white women, non-Hispanic black women admitted postpartum were at 27% greater risk of severe maternal morbidity (95% confidence interval, 24%-30%) whereas Hispanic women were at 10% lower risk (95% confidence interval, 7%-13%). In the adjusted model, non-Hispanic black women were at 16% greater risk for severe maternal morbidity during readmission than non-Hispanic white women (95% confidence interval, 10%-22%), whereas Hispanic women were at 7% lower risk (95% confidence interval, 1%-12%). Differences in severe maternal morbidity risk between other racial groups and non-Hispanic white women were not significant. In addition to overall morbidity, non-Hispanic black women were at significantly greater risk for eclampsia, acute respiratory distress syndrome, and renal failure than other racial groups (P<.05 all). Black women were at 126% greater risk for pulmonary edema/acute heart failure than white women (95% confidence interval, 117%-136%).

CONCLUSION

Black women were more likely (1) to be readmitted postpartum, (2) to suffer severe maternal morbidity during readmission, and (3) to suffer life threatening complications such as pulmonary edema/acute heart failure. At-risk women including black women with cardiovascular risk factors may benefit from short-term postpartum follow-up.

摘要

背景

产妇种族可能是产后再入院和相关不良结局的一个重要危险因素。

目的

确定种族与产后再入院期间严重并发症的关系。

研究设计

本重复横断面分析使用了 2012 年至 2014 年医疗保健成本和利用项目中的全国(全国)住院患者样本。根据疾病控制和预防中心的标准,确定了分娩后住院后出院后再次入院的 15-54 岁产妇。种族和族裔被描述为非西班牙裔白人、非西班牙裔黑人、西班牙裔、亚洲或太平洋岛民、美国原住民、其他和未知。确定了按种族划分的再入院总体风险。分析了种族之间再入院期间严重产妇发病率的风险。还按种族分析了个别结局,包括肺水肿/急性心力衰竭和中风。使用包括人口统计学、医院因素和合并症风险在内的对数线性回归模型,分析了产后再入院期间严重产妇发病率的风险。

结果

在 1130 万例分娩中,分析了 2012 年至 2014 年期间出院的 207730 名(1.8%)产妇,其中包括 96670 名非西班牙裔白人、47015 名非西班牙裔黑人、和 33410 名西班牙裔妇女。与非西班牙裔白人妇女相比,非西班牙裔黑人妇女再入院的风险高 80%(95%置信区间,79%-82%),而西班牙裔妇女的再入院风险低 11%(95%置信区间,10%-12%)。在未调整的分析中,与非西班牙裔白人妇女相比,非西班牙裔黑人妇女再入院时严重产妇发病率高 27%(95%置信区间,24%-30%),而西班牙裔妇女的发病率低 10%(95%置信区间,7%-13%)。在调整后的模型中,与非西班牙裔白人妇女相比,非西班牙裔黑人妇女再入院期间发生严重产妇发病率的风险高 16%(95%置信区间,10%-22%),而西班牙裔妇女的风险低 7%(95%置信区间,1%-12%)。其他种族群体与非西班牙裔白人妇女之间严重产妇发病率风险的差异不显著。除整体发病率外,非西班牙裔黑人妇女发生子痫、急性呼吸窘迫综合征和肾衰竭的风险明显高于其他种族群体(均<.05)。黑人妇女发生肺水肿/急性心力衰竭的风险比白人妇女高 126%(95%置信区间,117%-136%)。

结论

黑人妇女(1)更有可能再次入院,(2)在再入院期间出现严重的产妇发病率,(3)出现危及生命的并发症,如肺水肿/急性心力衰竭。包括黑人妇女在内的有心血管风险因素的高危妇女可能受益于产后短期随访。

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