1UC San Diego Moores Cancer Center.
2Duke Cancer Institute.
J Natl Compr Canc Netw. 2019 Feb;17(2):171-189. doi: 10.6004/jnccn.2019.0008.
As treatment of HIV has improved, people living with HIV (PLWH) have experienced a decreased risk of AIDS and AIDS-defining cancers (non-Hodgkin's lymphoma, Kaposi sarcoma, and cervical cancer), but the risk of Kaposi sarcoma in PLWH is still elevated about 500-fold compared with the general population in the United States. The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for AIDS-Related Kaposi Sarcoma provide diagnosis, treatment, and surveillance recommendations for PLWH who develop limited cutaneous Kaposi sarcoma and for those with advanced cutaneous, oral, visceral, or nodal disease.
随着 HIV 的治疗得到改善,HIV 感染者(PLWH)患艾滋病和艾滋病定义性癌症(非霍奇金淋巴瘤、卡波西肉瘤和宫颈癌)的风险降低,但与美国普通人群相比,PLWH 患卡波西肉瘤的风险仍高出约 500 倍。美国国家综合癌症网络(NCCN)艾滋病相关卡波西肉瘤临床实践指南(NCCN 指南)为出现局限性皮肤卡波西肉瘤的 PLWH 以及出现晚期皮肤、口腔、内脏或淋巴结疾病的 PLWH 提供了诊断、治疗和监测建议。