Fewson C A
Department of Biochemistry, University of Glasgow, U.K.
FEMS Microbiol Rev. 1988 Apr-Jun;4(2):85-110. doi: 10.1111/j.1574-6968.1988.tb02737.x.
This review highlights the diversity of prokaryotic and eukaryotic microorganisms that can metabolise mandelate and it describes how a wide range of compounds related to mandelate is formed in many environments. The chief aspects that are summarised include the various pathways whereby mandelate and its structural analogues are converted into catechol or protocatechuate, the properties of the enzymes that are involved in the pathways, and the regulation and genetics of the pathways. The review incorporates the idea that the study of peripheral metabolic pathways is particularly useful for illuminating evolutionary speculations and it concludes with a list of questions that need to be answered.
本综述强调了能够代谢扁桃酸盐的原核和真核微生物的多样性，并描述了在许多环境中如何形成与扁桃酸盐相关的多种化合物。总结的主要方面包括扁桃酸盐及其结构类似物转化为儿茶酚或原儿茶酸的各种途径、这些途径中所涉及酶的特性，以及这些途径的调控和遗传学。该综述纳入了这样一种观点，即对周边代谢途径的研究对于阐明进化推测特别有用，并以一系列需要回答的问题作为结尾。
