Ghazal Asswad Randa, Harrison Anna, Hans Paul S, Buzatu Casandra
The University of Liverpool, School of Medicine, Liverpool L69 3GE, UK.
ENT Department, Blackpool Teaching Hospitals NHS Trust, Blackpool FY3 8NR, UK.
J Surg Case Rep. 2019 Feb 8;2019(2):rjz017. doi: 10.1093/jscr/rjz017. eCollection 2019 Feb.
Behçet's disease (BD) is a rare complex multisystem inflammatory condition characterized by the triad of symptoms: aphthous ulcers of the mouth and genitalia and uveitis.
We present the case of a 31-year-old Caucasian male who had a prolonged journey from first presentation until diagnosis of BD. For 11 years, he presented symptoms affecting the oral cavity and oropharynx, with worsening odynophagia and dysphagia and ultimately, development of stridor. Flexible laryngoscopy showed significant laryngopharyngeal ulceration and scarring. Treatment was with colchicine, corticosteroids and azathioprine and supervised by one of three newly established BD Centres of Excellence in the UK.
Although uncommon, ENT manifestations in patients with BD should be taken into consideration to allow for early recognition and treatment of what can become a life-threatening condition. In such situations, early referral to a BD Centre of Excellence is essential to provide confirmation of diagnosis and supervision of treatment.
白塞病（BD）是一种罕见的复杂多系统炎症性疾病，其特征为三联征症状：口腔和生殖器阿弗他溃疡以及葡萄膜炎。
我们呈现一名31岁白种男性的病例，从首次出现症状到被诊断为白塞病经历了漫长过程。11年来，他出现影响口腔和口咽的症状，吞咽疼痛和吞咽困难不断加重，最终出现喘鸣。纤维喉镜检查显示喉咽有明显溃疡和瘢痕形成。采用秋水仙碱、皮质类固醇和硫唑嘌呤进行治疗，并由英国新设立的三个卓越白塞病中心之一进行监督。
尽管不常见，但白塞病患者的耳鼻喉科表现应予以考虑，以便早期识别并治疗可能危及生命的病情。在这种情况下，尽早转诊至卓越白塞病中心对于确诊和治疗监督至关重要。
