Dilsen N
Istanbul University, Istanbul School of Medicine, Turkey.
Rev Rhum Engl Ed. 1996 Jul-Sep;63(7-8):512-9.
I have tried to outline the history and development of Behçet's disease, which was first described in 1937 by Hulûsi Behçet, a Turkish Professor of Dermatology. The clinical picture is a triple symptom complex consisting of relapsing aphthous ulcers in the mouth and over the genitalia, and hypopion iritis. I have divided the developmental history of Behçet's disease into three periods: pre-Behçet, Behçet, and post-Behçet. Although similar clinical manifestations were mentioned in Hippocratic writings, clear examples of the symptomatic triad were not reported until the first quarter of this century. Since 1937, Behçet's disease has been a focus of active research. Exciting results concerning the genetics, immunology, molecular biology, diagnosis, and treatment of Behçet's disease have been obtained. It is hoped that the near future will bring additional discoveries to help solving difficulties in Behçet's disease.
我已尽力概述白塞病的历史与发展，该病于1937年由土耳其皮肤科教授胡卢西·白塞首次描述。其临床表现为一种三联征，包括口腔和生殖器复发性阿弗他溃疡以及前房积脓性虹膜炎。我将白塞病的发展历史分为三个时期：白塞病之前、白塞病时期以及白塞病之后。尽管希波克拉底的著作中提到过类似的临床表现，但直到本世纪上半叶才报道有明确的三联征症状实例。自1937年以来，白塞病一直是积极研究的焦点。在白塞病的遗传学、免疫学、分子生物学、诊断和治疗方面已取得了令人振奋的成果。希望在不久的将来能有更多发现，以帮助解决白塞病方面的难题。
