Vagios Ilias, Nonni Aphrodite, Liakea Aliki, Constantinidou Anastasia, Kontos Michael
First Department of Surgery, Laiko Hospital, National and Kapodistrian University of Athens, Athens 11527, Greece.
First Department of Pathology, National and Kapodistrian University of Athens, Athens 11527, Greece.
J Surg Case Rep. 2019 Feb 8;2019(2):rjz023. doi: 10.1093/jscr/rjz023. eCollection 2019 Feb.
Intraductal papilloma is a benign neoplasm rarely found in the male breast. In this report, we present the case of a 55-year-old Caucasian man who presented with spontaneous bloody nipple discharge of the right breast. Ultrasonic and mammographic investigations revealed a sub-centimetre solid mass within a dilated duct. He underwent a total duct excision. Histopathologic examination confirmed a benign intraductal papilloma with no evidence of atypia or malignancy. A systematic review of the literature revealed six published cases of intraductal papillomas in men. Clinical presentation is the same as in women with single duct blood stained discharge being the most common presenting symptom. Surgical excision offers both histologic confirmation and definitive treatment. There is one case where the lump was not removed and progressed to malignancy years later. Male intraductal papillomas may be associated to medical treatments with hormonal activity given for other reasons or endocrine abnormalities.
导管内乳头状瘤是一种罕见于男性乳腺的良性肿瘤。在本报告中，我们呈现了一名55岁白种男性的病例，该患者出现右侧乳腺自发性血性乳头溢液。超声和乳腺钼靶检查显示在扩张导管内有一个小于1厘米的实性肿块。他接受了全导管切除术。组织病理学检查证实为良性导管内乳头状瘤，无异型性或恶性证据。对文献的系统回顾发现有6例男性导管内乳头状瘤的报道。临床表现与女性相同，单导管血性溢液是最常见的症状。手术切除既能提供组织学确诊，也是确定性治疗。有1例肿块未切除，数年后进展为恶性肿瘤。男性导管内乳头状瘤可能与因其他原因进行的具有激素活性的医学治疗或内分泌异常有关。
