Bharti Sushma, Bharti Jyotsna Naresh, Vishnoi Jeewan Ram, Soudamini Arsha B
Department of Pathology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Department of Surgical Oncology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
J Family Community Med. 2020 Sep-Dec;27(3):216-218. doi: 10.4103/jfcm.JFCM_230_20. Epub 2020 Sep 25.
Male breast cancer is itself a very rare condition and represents 0.5%-1% of all breast cancers diagnosed. Atypical ductal hyperplasia (ADH), intraductal papilloma (IP), and ductal carcinoma are also very rare in a male breast. Only a few cases of ADH with gynecomastia have been reported in English literature until now. Here, we report a rare case of an IP with ADH associated with gynecomastia in an elderly male, who complained of right nipple pain, discharge, and tiny retroareolar mass. Mammography showed a subareolar nodule graded as the Breast Imaging-Reporting and Data System 4B. It is difficult to differentiate, both clinically and radiologically, between benign and malignant papillary lesions and invasive carcinoma, because of the similarity of findings. Hence, any male with palpable unilateral hard fixed lesions in the retroareolar region with complaints of nipple discharge, skin changes, or axillary lymphadenopathy should have a histopathological evaluation.
男性乳腺癌本身是一种非常罕见的疾病，占所有确诊乳腺癌的0.5%-1%。非典型导管增生（ADH）、导管内乳头状瘤（IP）和导管癌在男性乳腺中也非常罕见。迄今为止，英文文献中仅报道了少数几例伴有男性乳房肥大的ADH病例。在此，我们报告一例罕见的老年男性IP合并ADH并伴有男性乳房肥大的病例，该患者主诉右乳头疼痛、溢液及乳晕后微小肿块。乳腺钼靶检查显示乳晕下结节，分类为乳腺影像报告和数据系统4B级。由于检查结果相似，在临床和放射学上很难区分良性和恶性乳头状病变以及浸润性癌。因此，任何乳晕后区域可触及单侧坚硬固定病变、伴有乳头溢液、皮肤改变或腋窝淋巴结肿大主诉的男性都应进行组织病理学评估。
