用于青光眼治疗的 Xen 植入物：文献综述
XEN Implant for Glaucoma Treatment: A Review of the Literature.
作者信息
Chatzara Aikaterini, Chronopoulou Irini, Theodossiadis George, Theodossiadis Panagiotis, Chatziralli Irini
机构信息
a Medical School , National and Kapodistrian University of Athens , Athens , Greece.
b 2nd Department of Ophthalmology , National and Kapodistrian University of Athens , Athens , Greece.
出版信息
Semin Ophthalmol. 2019;34(2):93-97. doi: 10.1080/08820538.2019.1581820. Epub 2019 Feb 21.
PURPOSE
The purpose of this review is to summarize current knowledge on XEN implant for the treatment of glaucoma.
METHODS
A comprehensive literature review has been performed regarding XEN implant and its use on glaucoma management. Forty-two articles were checked and 37 were found to be relevant. Out of them, 21 were excluded as being case reports and reviews and the remaining 16 were eligible for the purpose of our review.
RESULTS
There was a significant reduction in intraocular pressure as well as in the number of medications needed in glaucoma patients treated with XEN implant either alone or combined with cataract surgery. In addition, combination of XEN implant with Baerveldt tubes has been shown to be beneficial in cases of refractory glaucoma, although complications may be present in this technique. Moreover, uveitic glaucoma may be a potential application of XEN implant.
CONCLUSIONS
XEN implant devices have been developed as a surgical alternative for glaucomatous patients and are expected to play an important role in the management of glaucoma in the future.
目的
本综述的目的是总结关于XEN植入物治疗青光眼的现有知识。
方法
已对XEN植入物及其在青光眼治疗中的应用进行了全面的文献综述。检查了42篇文章，发现37篇相关。其中，21篇因属病例报告和综述而被排除，其余16篇符合我们综述的目的。
结果
单独使用XEN植入物或与白内障手术联合使用时，接受治疗的青光眼患者的眼压以及所需药物数量均显著降低。此外，XEN植入物与Baerveldt管联合使用已被证明在难治性青光眼病例中有益，尽管该技术可能存在并发症。此外，葡萄膜炎性青光眼可能是XEN植入物的一个潜在应用领域。
结论
XEN植入装置已被开发作为青光眼患者的一种手术替代方案，预计未来将在青光眼治疗中发挥重要作用。
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