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Xen45 凝胶支架经内切开术处理内孔阻塞:病例报告。

Xen45 gel stent ab interno trimming for ostium occlusion: case report.

机构信息

Department of Surgical Sciences, Eye Clinic, University of Cagliari, Via Ospedale 48, 09124, Cagliari, Italy.

出版信息

BMC Ophthalmol. 2021 Dec 27;21(1):446. doi: 10.1186/s12886-021-02207-8.

DOI:10.1186/s12886-021-02207-8
PMID:34961501
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8711208/
Abstract

BACKGROUND

Despite the XEN gel stent low-risk profile, various complications following the implant have been described, including internal and external occlusion, with a consequent postoperative rise in intraocular pressure (IOP). In this case report we aimed to present a XEN45 stent internal occlusion successfully treated by trimming in situ its proximal end with a 25 G vitreous scissors using a bimanual technique.

CASE PRESENTATION

A 63-year-old male patient affected by primary open angle glaucoma (IOP = 25 mmHg) and a full thickness macular hole in his right eye, underwent ab-interno Xen gel stent implantation and, 1 month later, a 25 G vitrectomy surgery. Despite a significant IOP reduction after stent implant, 6 days after vitrectomy, IOP increased (25 mmHg) and the conjunctival bleb flattened following occlusion of stent internal ostium by a clot of presumed fibrinous material. The Nd:YAG laser failed to remove the clot, so that we decided to snip a small bit of the proximal end of the Xen tube (about 0,5 mm length) with a 25 G vitreous scissors, using a bimanual technique. In the postoperative day 1 and month 1, the IOP was 8 mmHg and 12 mmHg, respectively. The Anterior Segment OCT confirmed a functional, layered, filtering bleb, and the normal appearance and patency of the XEN proximal segment. No side effects from the intervention were observed.

CONCLUSIONS

Ab interno trimming with vitreous scissors of the occluded proximal end of the XEN stent may represent a safe, rapid and efficient method to restore aqueous humor subconjunctival drainage.

摘要

背景

尽管 XEN 凝胶支架具有低风险特征,但植入后仍出现各种并发症,包括内、外阻塞,随之导致术后眼内压(IOP)升高。在本病例报告中,我们旨在介绍一种通过使用双手技术用 25G 玻璃体剪刀在原位修剪其近端来成功治疗 XEN45 支架内阻塞的方法。

病例介绍

一名 63 岁男性患者患有原发性开角型青光眼(IOP=25mmHg)和右眼全层黄斑裂孔,接受了内路 XEN 凝胶支架植入术,1 个月后接受了 25G 玻璃体切除术。尽管支架植入后 IOP 显著降低,但在玻璃体切除术后 6 天,IOP 升高(25mmHg),并在支架内口被推测为纤维蛋白物质的凝块阻塞后,结膜滤泡变平。Nd:YAG 激光未能清除凝块,因此我们决定使用 25G 玻璃体剪刀通过双手技术剪断 Xen 管近端的一小部分(约 0.5mm 长度)。术后第 1 天和第 1 个月,IOP 分别为 8mmHg 和 12mmHg。前节 OCT 证实了一个功能分层的滤过泡,XEN 近端段外观和通畅性正常。未观察到干预的副作用。

结论

使用玻璃体剪刀对内路修剪阻塞的 XEN 支架近端可能是一种安全、快速和有效的方法,可恢复房水经结膜下引流。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a583/8711208/54d651ad2859/12886_2021_2207_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a583/8711208/801b26740ad4/12886_2021_2207_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a583/8711208/854252977aa6/12886_2021_2207_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a583/8711208/8797f0e4f9c6/12886_2021_2207_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a583/8711208/f3305ea2aa05/12886_2021_2207_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a583/8711208/54d651ad2859/12886_2021_2207_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a583/8711208/801b26740ad4/12886_2021_2207_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a583/8711208/854252977aa6/12886_2021_2207_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a583/8711208/8797f0e4f9c6/12886_2021_2207_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a583/8711208/f3305ea2aa05/12886_2021_2207_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a583/8711208/54d651ad2859/12886_2021_2207_Fig5_HTML.jpg

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Technique of Xen Implant Revision Surgery and the Surgical Outcomes: A Retrospective Interventional Case Series.异种植入物翻修手术技术与手术结果:一项回顾性介入病例系列研究。
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