Finlay B B, Falkow S
Department of Medical Microbiology, Stanford University School of Medicine, California 94305.
Microbiol Sci. 1988 Nov;5(11):324-8.
Salmonella species can cause diseases ranging in severity from acute gastroenteritis to typhoid fever. These bacteria are considered as intracellular pathogens and produce several products which are required for entry and survival in the intracellular environment, in addition to factors necessary for existence in the gastrointestinal tract and the outside environment. The virulence factors used by these bacteria to cause these diseases are complex, and only recently have we begun to characterize these factors and determine the contribution they make to Salmonella virulence.
沙门氏菌可引发从急性肠胃炎到伤寒热等一系列严重程度不同的疾病。这些细菌被视为细胞内病原体，除了在胃肠道和外部环境中生存所需的因素外，还会产生几种在细胞内环境中进入和存活所必需的产物。这些细菌用于引发这些疾病的毒力因子很复杂，直到最近我们才开始对这些因子进行表征，并确定它们对沙门氏菌毒力的贡献。
