Department of Urology, The third the People's Hospital of Bengbu, 38# Shengli Road, Bengbu, Anhui Province, China.
Department of Nursing, The third the People's Hospital of Bengbu, 38# Shengli Road, Bengbu, Anhui Province, China.
BMC Nephrol. 2019 Feb 21;20(1):62. doi: 10.1186/s12882-019-1256-7.
Neoplasms originating in the renal capsule are very rare. Benign fibrous histiocytoma(BFH) most commonly occurs in the dermis and subcutis, few cases of this tumor appear in the renal capsule. In particular, BFH larger than 20 cm are scarce. Here we report a rare huge one measuring 23 × 13 × 7 cm.
We report a 64-year-old man who presented with a few-months history of dull pain in the right groin. The tumor had its point of origin in the renal capsule which is a rare condition. Histologically, the tumor was composed of intersecting fascicles of fibroblastic cells forming a "storiform" pattern. Immunohistochemical studies were also performed, ultimately leading to the diagnosis of BFH. The patient was treated with radical nephrectomy. No recurrence was detected 4 months after surgery.
BFH arising from the renal capsule was very rare. In particular, the case of more than twenty centimeters is extremely rare. The clinical presentation of renal BFH might be only a mass. However, differential diagnosis from renal cell carcinoma proved to be impossible before surgical intervention. It is difficult to diagnose only by means of histopathology, but the immunohistochemical method can provide a clear and definite diagnosis.
起源于肾包膜的肿瘤非常罕见。良性纤维组织细胞瘤(BFH)最常发生于真皮和皮下组织,少数情况下也会出现在肾包膜。特别是大于 20cm 的 BFH 更为罕见。本文报道了一例罕见的巨大 BFH,大小为 23×13×7cm。
我们报告了一例 64 岁男性,右侧腹股沟区隐痛数月。肿瘤起源于肾包膜,这是一种罕见的情况。组织学上,肿瘤由成纤维细胞交叉束组成,形成“交织状”模式。还进行了免疫组织化学研究,最终诊断为 BFH。患者接受了根治性肾切除术。术后 4 个月未发现复发。
起源于肾包膜的 BFH 非常罕见。特别是超过二十厘米的病例极其罕见。肾 BFH 的临床表现可能仅为肿块。然而,在手术干预之前,与肾细胞癌的鉴别诊断是不可能的。仅通过组织病理学诊断较为困难,但免疫组织化学方法可以提供明确的诊断。