Freyler H, Klemen U
Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1978 Jul 4;207(1):27-39. doi: 10.1007/BF00414491.
Penetrating corneal incisions of various sizes and forms were microsurgically glued onto 48 rabbit eyes by means of fibrinogen-plasma cryoprecipitate with or without 10x0 nylon sutures. Linear or curved penetrating corneal cuts up to 4 mm in length could be immediately closed water tight by pure gluing and without development of anterior synechiae. The suturing of oblique cuts may prove problematic. The more oblique such cuts were, the better the results they yielded after gluing. In cases of linear penetrating corneal incisions exceeding 4 mm in length, and in star-shaped wounds with radiants over 3 mm in length, anterior synechiae could only be avoided by application of additional sutures. Pure or additional gluing of corneal penetrating cuts accelerated wound healing, but was followed by broader scars than after pure suturing. Hence, the gluing of certain types of penetrating corneal wounds by means of fibrin can be applied only as an auxiliary procedure to microsurgical wound closure with sutures.
通过纤维蛋白原 - 血浆冷沉淀物,在有或没有10 - 0尼龙缝线的情况下,将各种大小和形状的穿透性角膜切口显微手术粘贴到48只兔眼上。长达4毫米的线性或弯曲穿透性角膜切口可以通过单纯粘贴立即实现水密闭合,且不会形成前粘连。斜切口的缝合可能存在问题。切口越斜,粘贴后的效果越好。对于长度超过4毫米的线性穿透性角膜切口以及辐射长度超过3毫米的星形伤口,只有通过额外缝合才能避免前粘连。角膜穿透切口的单纯粘贴或额外粘贴可加速伤口愈合,但与单纯缝合后相比,会形成更宽的瘢痕。因此,利用纤维蛋白对某些类型的穿透性角膜伤口进行粘贴只能作为显微手术缝线伤口闭合的辅助程序。