Department of Cardiovascular Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Cardiovascular Rehabilitation and Fitness, Juntendo University Hospital, Tokyo, Japan.
Geriatr Gerontol Int. 2019 Apr;19(4):287-292. doi: 10.1111/ggi.13617. Epub 2019 Feb 22.
The Kihon Checklist is a useful screening tool for assessing frailty in older individuals. However, the clinical significance of the Kihon Checklist in cardiac rehabilitation patients remains unclear. The present study aimed to evaluate the relationship between the Kihon Checklist and the clinical parameters in patients who participated in cardiac rehabilitation.
We enrolled 845 consecutive patients (584 men, mean age 71 years) who participated in cardiac rehabilitation at Juntendo University Hospital, Tokyo, Japan, between November 2015 and October 2017. The patients were divided into non-frailty (n = 287), pre-frailty (n = 270) and frailty (n = 288) groups according to their Kihon Checklist scores. Cardiopulmonary exercise testing was carried out in 302 patients.
The frailty group was older and had a higher prevalence of history of heart failure than the non-frailty group, although left ventricular ejection fraction did not differ significantly between groups. Nutritional index, trunk and limb muscle mass, lean body weight, and grip strength were significantly lower in the frailty and pre-frailty groups than those in the non-frailty group. In the cardiopulmonary exercise test, a stepwise significant decrease in peak oxygen uptake was observed across the three groups (non-frailty 17.2 ± 3.6, pre-frailty 16.0 ± 3.4, frailty 14.4 ± 3.5 mL/kg/min, P < 0.01). Multivariate regression analyses showed that the Kihon Checklist score was significantly and independently associated with peak oxygen uptake (r = -0.34, P < 0.0001).
The Kihon Checklist, which was associated with frailty and exercise tolerance, could be used as a clinical assessment method for patients who participated in cardiac rehabilitation. Geriatr Gerontol Int 2019; 19: 287-292.
《健康基本 checklist》是一种评估老年人虚弱程度的有用筛查工具。然而,该检查表在心脏康复患者中的临床意义尚不清楚。本研究旨在评估《健康基本 Checklist》与参加心脏康复患者的临床参数之间的关系。
我们纳入了 2015 年 11 月至 2017 年 10 月期间在日本东京顺天堂大学医院参加心脏康复的 845 例连续患者(男性 584 例,平均年龄 71 岁)。根据《健康基本 Checklist》评分,患者被分为非虚弱组(n=287)、虚弱前期组(n=270)和虚弱组(n=288)。对 302 例患者进行心肺运动试验。
虚弱组年龄较大,心力衰竭史发生率高于非虚弱组,尽管左心室射血分数在各组间无显著差异。虚弱组和虚弱前期组的营养指数、躯干和四肢肌肉质量、瘦体重和握力明显低于非虚弱组。在心肺运动试验中,三组的峰值摄氧量呈逐步显著下降(非虚弱组 17.2±3.6、虚弱前期组 16.0±3.4、虚弱组 14.4±3.5mL/kg/min,P<0.01)。多元回归分析显示,《健康基本 Checklist》评分与峰值摄氧量显著相关(r=-0.34,P<0.0001)。
与虚弱和运动耐量相关的《健康基本 Checklist》可作为参加心脏康复患者的临床评估方法。