a Pediatric Department, Faculty of Medicine , Mansoura University , Mansoura , Egypt.
b Medical School , University of Nicosia , Nicosia , Cyprus.
Nutr Cancer. 2019;71(3):524-530. doi: 10.1080/01635581.2019.1577980. Epub 2019 Feb 22.
Overweight and obesity in the pediatric population remains a growing worldwide health burden. The extent to which this trend extends to childhood cancer survivors (CCS) remains less well explored. We conducted a retrospective observational study from a single institution in Saudi Arabia to estimate the prevalence of overweight and obese status among CCS over a five-year period. A total of 91 CCS patients were identified, 63 of whom had complete weight data from their treatment to the time of the study. Of these patients, 29 (46.0%) were found to be overweight or obese [body mass index (BMI) ≥85th percentile] at the time of the study. Of these patients, this rate was particularly high for patients who were female, older at the time of diagnosis (>6 years) (72.8%) and among pubescent patients (Tanner 3-5 at diagnosis). The rate of overweight and obesity increased from 31.7% immediately after the end of treatment (average age of 7.1 years) to 36.5% one year after. Thereafter, these percentages increased to approximately 38% over the 5-year follow-up period and increased beyond that up to 46%. A high prevalence of overweight and obesity among CCS was found at the end of their treatment with an observed increasing trend towards overweight and obesity in the following years, suggesting the need for early and continuous intensive intervention and frequent dietary evaluation.
在儿科人群中，超重和肥胖仍然是一个日益严重的全球健康负担。这种趋势在儿童癌症幸存者（CCS）中扩展到何种程度，尚未得到充分探索。我们在沙特阿拉伯的一家单机构进行了一项回顾性观察研究，以估计在五年内 CCS 中超重和肥胖状态的患病率。共确定了 91 名 CCS 患者，其中 63 名患者在治疗期间到研究时具有完整的体重数据。在这些患者中，有 29 名（46.0%）在研究时超重或肥胖[体重指数（BMI）≥第 85 百分位数]。在这些患者中，女性、诊断时年龄较大（>6 岁）（72.8%）和青春期患者（诊断时 Tanner 3-5 期）的这一比例特别高。超重和肥胖的发生率从治疗结束时的 31.7%（平均年龄为 7.1 岁）增加到 1 年后的 36.5%。此后，这些百分比在 5 年的随访期间增加到约 38%，并在此基础上增加到 46%。在治疗结束时发现 CCS 中有很高的超重和肥胖患病率，并且在随后的几年中观察到超重和肥胖的趋势呈上升趋势，这表明需要早期和持续的强化干预以及频繁的饮食评估。
