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患者特异性三维打印心脏模型有益于复杂先天性心脏病的术前规划。

Patient-specific three-dimensional printed heart models benefit preoperative planning for complex congenital heart disease.

机构信息

Department of Heart Center, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, 310058, China.

School of Mechanical Engineering, Zhejiang University, Hangzhou, 310058, China.

出版信息

World J Pediatr. 2019 Jun;15(3):246-254. doi: 10.1007/s12519-019-00228-4. Epub 2019 Feb 22.

Abstract

BACKGROUND

Preoperative planning for children with congenital heart diseases remains crucial and challenging. This study aimed to investigate the roles of three-dimensional printed patient-specific heart models in the presurgical planning for complex congenital heart disease.

METHODS

From May 2017 to January 2018, 15 children diagnosed with complex congenital heart disease were included in this study. Heart models were printed based on computed tomography (CT) imaging reconstruction by a 3D printer with photosensitive resin using the stereolithography apparatus technology. Surgery options were first evaluated by a sophisticated cardiac surgery group using CT images only, and then surgical plans were also set up based on heart models.

RESULTS

Fifteen 3D printed heart models were successfully generated. According to the decisions based on CT, 13 cases were consistent with real options, while the other 2 were not. According to 3D printed heart models, all the 15 cases were consistent with real options. Unfortunately, one child diagnosed with complete transposition of great arteries combined with interruption of aortic arch (type A) died 5 days after operation due to postoperative low cardiac output syndrome. The cardiologists, especially the younger ones, considered that these 3D printed heart models with tangible, physical and comprehensive illustrations were beneficial for preoperative planning of complex congenital heart diseases.

CONCLUSION

3D printed heart models are beneficial and promising in preoperative planning for complex congenital heart diseases, and are able to help conform or even improve the surgery options.

摘要

背景

儿童先天性心脏病的术前规划仍然至关重要且具有挑战性。本研究旨在探讨三维打印患者特定心脏模型在复杂先天性心脏病术前规划中的作用。

方法

本研究纳入了 2017 年 5 月至 2018 年 1 月期间被诊断为复杂先天性心脏病的 15 名儿童。心脏模型是通过立体光刻设备技术使用光敏树脂在 3D 打印机上基于计算机断层扫描(CT)成像重建打印的。首先,一个复杂的心脏外科团队仅使用 CT 图像评估手术方案,然后再根据心脏模型制定手术计划。

结果

成功生成了 15 个 3D 打印心脏模型。根据基于 CT 的决策,13 例与实际方案一致,而另外 2 例则不一致。根据 3D 打印的心脏模型,所有 15 例均与实际方案一致。不幸的是,一名被诊断为完全性大动脉转位合并主动脉弓中断(A型)的儿童在术后 5 天因术后低心输出量综合征死亡。心脏科医生,尤其是年轻医生,认为这些具有有形、物理和全面说明的 3D 打印心脏模型有助于复杂先天性心脏病的术前规划。

结论

3D 打印心脏模型有助于复杂先天性心脏病的术前规划,并且有助于确认甚至改进手术方案。

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