Yaneva Antoniya, Shopova Dobromira, Bakova Desislava, Mihaylova Anna, Kasnakova Petya, Hristozova Maria, Semerdjieva Maria
Department of Medical Informatics, Biostatistics and eLearning, Faculty of Public Health, Medical University, 4000 Plovdiv, Bulgaria.
Department of Prosthetic Dentistry, Faculty of Dental Medicine, Medical University, 4000 Plovdiv, Bulgaria.
Bioengineering (Basel). 2023 Aug 1;10(8):910. doi: 10.3390/bioengineering10080910.
The intensive development of technologies related to human health in recent years has caused a real revolution. The transition from conventional medicine to personalized medicine, largely driven by bioprinting, is expected to have a significant positive impact on a patient's quality of life. This article aims to conduct a systematic review of bioprinting's potential impact on health-related quality of life. A literature search was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A comprehensive literature search was undertaken using the PubMed, Scopus, Google Scholar, and ScienceDirect databases between 2019 and 2023. We have identified some of the most significant potential benefits of bioprinting to improve the patient's quality of life: personalized part production; saving millions of lives; reducing rejection risks after transplantation; accelerating the process of skin tissue regeneration; homocellular tissue model generation; precise fabrication process with accurate specifications; and eliminating the need for organs donor, and thus reducing patient waiting time. In addition, these advances in bioprinting have the potential to greatly benefit cancer treatment and other research, offering medical solutions tailored to each individual patient that could increase the patient's chance of survival and significantly improve their overall well-being. Although some of these advancements are still in the research stage, the encouraging results from scientific studies suggest that they are on the verge of being integrated into personalized patient treatment. The progress in bioprinting has the power to revolutionize medicine and healthcare, promising to have a profound impact on improving the quality of life and potentially transforming the field of medicine and healthcare.
近年来,与人类健康相关的技术密集发展引发了一场真正的革命。从传统医学向个性化医学的转变在很大程度上由生物打印推动,预计将对患者的生活质量产生重大积极影响。本文旨在对生物打印对健康相关生活质量的潜在影响进行系统综述。根据系统评价和荟萃分析的首选报告项目(PRISMA)指南进行了文献检索。在2019年至2023年期间,使用PubMed、Scopus、谷歌学术和ScienceDirect数据库进行了全面的文献检索。我们确定了生物打印改善患者生活质量的一些最重要的潜在益处:个性化部件生产;挽救数百万人的生命;降低移植后的排斥风险;加速皮肤组织再生过程;生成同细胞组织模型;具有精确规格的精确制造过程;消除对器官捐赠者的需求,从而减少患者等待时间。此外,生物打印的这些进展有可能极大地惠及癌症治疗和其他研究,提供针对每个患者的医疗解决方案,这可能增加患者的生存机会并显著改善他们的整体健康状况。尽管其中一些进展仍处于研究阶段,但科学研究的令人鼓舞的结果表明,它们即将融入个性化患者治疗中。生物打印的进展有能力彻底改变医学和医疗保健,有望对提高生活质量产生深远影响,并有可能改变医学和医疗保健领域。