Department of Biology & Center for Environmental and Marine Studies (CESAM), University of Aveiro, 3810-193 Aveiro, Portugal; Department of Mechanical Engineering & Center for Mechanical Technology and Automation (TEMA), University of Aveiro, 3810-193 Aveiro, Portugal.
Department of Mechanical Engineering & Center for Mechanical Technology and Automation (TEMA), University of Aveiro, 3810-193 Aveiro, Portugal.
Comp Biochem Physiol C Toxicol Pharmacol. 2019 May;219:103-115. doi: 10.1016/j.cbpc.2019.02.008. Epub 2019 Feb 21.
The widespread use of Carbon nanotubes (CNTs) has been increasing exponentially, leading to a significant potential release into the environment. Nevertheless, the toxic effects of CNTs in natural aquatic systems are related to their ability to interact with abiotic compounds. Considering that salinity variations are one of the main challenges in the environment and thus may influence the behavior and toxicity of CNTs, a laboratory experiment was performed exposing the tube-building polychaete Diopatra neapolitana (Delle Chiaje 1841) for 28 days to pristine multi-walled carbon nanotube (MWCNTs) and carboxylated MWCNTs, maintained at control salinity 28 and low salinity 21. An innovative approach based on thermogravimetric analysis (TGA) was adopted for the first time to assess the presence of MWCNTs aggregates in the organisms. Both CNTs generated toxic impacts in terms of regenerative capacity, energy reserves and metabolic capacity as well as oxidative and neuro status, however greater toxic impacts were observed in polychaetes exposed to carboxylated MWCNTs. Moreover, both CNTs maintained under control salinity (28) generated higher toxic impacts in the polychaetes compared to individuals maintained under low salinity (21), indicating that exposed polychaetes tend to be more sensitive to the alteration induced by salinity variations on the chemical behavior of both MWCNTs in comparison to salt stress.
碳纳米管（CNTs）的广泛应用呈指数级增长，这导致它们有可能大量释放到环境中。然而，CNTs 在自然水生系统中的毒性效应与其与非生物化合物相互作用的能力有关。考虑到盐度变化是环境中的主要挑战之一，因此可能会影响 CNTs 的行为和毒性，进行了一项实验室实验，将管状体多毛类动物 Diopatra neapolitana（Delle Chiaje 1841）暴露于原始多壁碳纳米管（MWCNTs）和羧化 MWCNTs 中 28 天，MWCNTs 和羧化 MWCNTs 分别保持在对照盐度 28 和低盐度 21。首次采用基于热重分析（TGA）的创新方法来评估生物体中 MWCNTs 聚集体的存在。两种 CNTs 都在再生能力、能量储备和代谢能力以及氧化和神经状态方面产生了毒性影响，但暴露于羧化 MWCNTs 的多毛类动物表现出更大的毒性影响。此外，与在低盐度（21）下维持的个体相比，在对照盐度（28）下维持的两种 CNTs 对多毛类动物产生了更高的毒性影响，这表明暴露的多毛类动物对盐度变化引起的 CNTs 化学行为的改变比盐度胁迫更敏感。
