医院感染暴发与监测中鲍曼不动杆菌的基因分型

Genotyping of Acinetobacter baumannii in Nosocomial Outbreak and Surveillance.

作者信息

Vijayakumar Saranya, Veeraraghavan Balaji, Pragasam Agila K, Bakthavachalam Yamuna Devi

机构信息

Department of Clinical Microbiology, Christian Medical College, Vellore, Tamil Nadu, India.

出版信息

Methods Mol Biol. 2019;1946:17-22. doi: 10.1007/978-1-4939-9118-1_2.

DOI:10.1007/978-1-4939-9118-1_2

PMID:30798540

Abstract

Acinetobacter baumannii is considered to be an important nosocomial pathogen responsible for various outbreaks that have resulted in a need for effective epidemiological typing methods. Different typing methods are available for A. baumannii epidemiological studies. Currently, the phenotypic typing methods are not being used and replaced by various molecular methods. In this chapter, two important epidemiological typing methods, pulsed-field gel electrophoresis (PFGE) and multi-locus sequence typing (MLST), are discussed.

摘要

鲍曼不动杆菌被认为是一种重要的医院病原体，它导致了各种疫情爆发，因此需要有效的流行病学分型方法。有不同的分型方法可用于鲍曼不动杆菌的流行病学研究。目前，表型分型方法已不再使用，取而代之的是各种分子方法。在本章中，将讨论两种重要的流行病学分型方法，即脉冲场凝胶电泳（PFGE）和多位点序列分型（MLST）。