HIV合并感染中丙型肝炎病毒与弥漫性大B细胞淋巴瘤的直接抗病毒药物联合治疗：一例报告
Concomitant Treatment of Hepatitis C Virus and Diffuse Large B-Cell Lymphoma with Direct-Acting Antivirals in HIV Coinfection: A Case Report.
作者信息
Gallipani Alyssa, Cha Agnes, Berkowitz Leonard, Bakshi Anjali
机构信息
1 Corporate Pharmacy, RWJ Barnabas Health, West Orange, NJ, USA.
2 Arnold & Marie Schwartz College of Pharmacy, Brooklyn, NY, USA.
出版信息
J Int Assoc Provid AIDS Care. 2019 Jan-Dec;18:2325958218822062. doi: 10.1177/2325958218822062.
Abstract
This report describes a case of concomitant treatment of advanced diffuse large B-cell lymphoma with chemoimmunotherapy along with direct-acting antivirals for hepatitis C virus in a patient coinfected with HIV. The patient tolerated gemcitabine, dexamethasone, cisplatin, and rituximab and achieved sustained virologic response after treatment with ledipasvir/sofosbuvir.
摘要
本报告描述了一例同时感染HIV的患者，采用化疗免疫疗法联合直接作用抗病毒药物治疗丙型肝炎病毒，同时治疗晚期弥漫性大B细胞淋巴瘤的病例。该患者耐受吉西他滨、地塞米松、顺铂和利妥昔单抗，并在接受来迪派韦/索磷布韦治疗后实现了持续病毒学应答。
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