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额部纤维性脱发:一种新的自身免疫性疾病实体?

Frontal fibrosing alopecia: A new autoimmune entity?

机构信息

Universidad Icesi, Medical School, Cali, Colombia; GIRAT: Grupo de Investigación en Reumatología, Autoinmunidad y Medicina Traslacional, Fundación Valle Del Lili and Universidad Icesi, Cali, Colombia.

GIRAT: Grupo de Investigación en Reumatología, Autoinmunidad y Medicina Traslacional, Fundación Valle Del Lili and Universidad Icesi, Cali, Colombia.

出版信息

Med Hypotheses. 2019 Mar;124:13-16. doi: 10.1016/j.mehy.2019.01.021. Epub 2019 Jan 24.

Abstract

Frontal fibrosing alopecia (FFA) is a rare type of cicatricial alopecic band, with bilateral and symmetric progressive regression of the frontotemporal hairline. The specific mechanisms of development of FFA remain unknown. Due to several clues, including the presence of lymphocytic infiltrates and the association of FFA with other autoimmune disorders, we hypothesised that FFA may be a new autoimmune condition, and future research must be focused on this possible origin.

摘要

额部纤维性脱发(FFA)是一种罕见的瘢痕性脱发带,其特征是额颞部发际线双侧、对称进行性后退。FFA 的确切发病机制尚不清楚。鉴于几项线索,包括淋巴细胞浸润的存在和 FFA 与其他自身免疫性疾病的关联,我们推测 FFA 可能是一种新的自身免疫性疾病,未来的研究必须集中在这个可能的起源上。

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