Chico-Fernández M, Sánchez-Casado M, Barea-Mendoza J A, García-Sáez I, Ballesteros-Sanz M Á, Guerrero-López F, Quintana-Díaz M, Molina-Díaz I, Martín-Iglesias L, Toboso-Casado J M, Pérez-Bárcena J, Llompart-Pou J A
UCI de Trauma y Emergencias, Servicio de Medicina Intensiva, Hospital Universitario 12 de Octubre, Madrid, Spain.
Servicio de Medicina Intensiva, Hospital Virgen de la Salud, Toledo, Spain.
Med Intensiva (Engl Ed). 2020 May;44(4):210-215. doi: 10.1016/j.medin.2019.01.006. Epub 2019 Feb 21.
To analyze outcomes and factors related to mortality among very elderly trauma patients admitted to intensive care units (ICUs) participating in the Spanish trauma ICU registry.
A multicenter nationwide registry. Retrospective analysis. November 2012-May 2017.
Participating ICUs.
Trauma patients aged ≥80 years.
None.
The outcomes and influence of limitation of life sustaining therapy (LLST) were analyzed. Comparisons were established using the Wilcoxon test, Chi-squared test or Fisher's exact test as appropriate. Multiple logistic regression analysis was performed to analyze variables related to mortality. A p-value <0.05 was considered statistically significant.
The mean patient age was 83.4±3.3 years; 281 males (60.4%). Low-energy falls were the mechanisms of injury in 256 patients (55.1%). The mean ISS was 20.5±11.1, with a mean ICU stay of 7.45±9.9 days. The probability of survival based on the TRISS methodology was 69.8±29.7%. The ICU mortality rate was 15.5%, with an in-hospital mortality rate of 19.2%. The main cause of mortality was intracranial hypertension (42.7%). The ISS, the need for first- and second-tier measures to control intracranial pressure, and being admitted to the ICU for organ donation were independent mortality predictors. LLST was applied in 128 patients (27.9%). Patients who received LLST were older, with more severe trauma, and with more severe brain injury.
Very elderly trauma ICU patients presented mortality rates lower than predicted on the basis of the severity of injury.
分析入住参与西班牙创伤重症监护病房(ICU)登记系统的ICU的高龄创伤患者的预后及与死亡率相关的因素。
一项多中心全国性登记研究。回顾性分析。2012年11月至2017年5月。
参与研究的ICU。
年龄≥80岁的创伤患者。
无。
分析维持生命治疗(LLST)受限的预后及影响。根据情况使用Wilcoxon检验、卡方检验或Fisher精确检验进行比较。进行多因素逻辑回归分析以分析与死亡率相关的变量。p值<0.05被认为具有统计学意义。
患者平均年龄为83.4±3.3岁;男性281例(60.4%)。256例患者(55.1%)的致伤机制为低能量跌倒。平均损伤严重程度评分(ISS)为20.5±11.1,ICU平均住院时间为7.45±9.9天。根据创伤和损伤严重度评分系统(TRISS)方法计算的生存概率为69.8±29.7%。ICU死亡率为15.5%,住院死亡率为19.2%。主要死亡原因是颅内高压(42.7%)。ISS、控制颅内压所需的一级和二级措施以及因器官捐献入住ICU是独立的死亡预测因素。128例患者(27.9%)接受了LLST。接受LLST的患者年龄更大,创伤更严重,脑损伤更严重。
高龄创伤ICU患者的死亡率低于根据损伤严重程度预测的死亡率。