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保守治疗的肋骨骨折患者的发病率预测

Morbidity prediction in conservatively managed rib fracture patients.

作者信息

Ekestubbe Lovisa, Forssten Maximilian Peter, Cao Yang, Sarani Babak, Mohseni Shahin

机构信息

Department of Orthopedic Surgery, Orebro University Hospital, Orebro, Sweden.

School of Medical Sciences, Orebro University, Orebro, Sweden.

出版信息

Eur J Trauma Emerg Surg. 2025 Apr 29;51(1):184. doi: 10.1007/s00068-025-02860-4.

Abstract

PURPOSE

Rib fractures, common in blunt chest trauma, affect 10% of trauma patients and are linked to increased pulmonary morbidity and mortality. This study applies machine learning to identify predictors of complications in conservatively managed rib fracture patients.

METHODS

Data from the 2013-2021 American College of Surgeons' Trauma Quality Improvement Program included adults (≥ 18 years) with isolated thoracic injury from blunt trauma and conservatively managed rib fractures. Variables included demographics, comorbidities, injury severity, injury patterns, admission vitals, and complications. The permutation importance method identified top predictors of in-hospital complications.

RESULTS

Of 321,355 rib fracture patients, 183,303 (57.0%) had isolated rib fractures. The five primary predictors of complications in all rib fracture patients were age, Glasgow Coma Scale (GCS) on admission, Revised Cardiac Risk Index (RCRI), chronic obstructive pulmonary disease (COPD), and alcohol use disorder. For isolated rib fracture patients, the same predictors applied but in the order: age, RCRI, GCS, COPD, and alcohol use disorder. A logistic regression model using these predictors showed acceptable discriminative capacity for complications in the full cohort [AUC (95% CI): 0.72 (0.71-0.72)] and isolated rib fracture patients [AUC (95% CI): 0.72 (0.71-0.73)].

CONCLUSION

Cardiovascular risk, age, and level of consciousness on admission are key predictors of complications in conservatively managed rib fracture patients. Though complication rates remain low overall, elderly patients with multiple cardiovascular risk factors face a heightened risk of deterioration.

摘要

目的

肋骨骨折在钝性胸部创伤中很常见,影响10%的创伤患者,并与肺部发病率和死亡率的增加有关。本研究应用机器学习来识别保守治疗的肋骨骨折患者并发症的预测因素。

方法

2013 - 2021年美国外科医师学会创伤质量改进项目的数据包括因钝性创伤导致孤立性胸部损伤且接受保守治疗的肋骨骨折的成年人(≥18岁)。变量包括人口统计学、合并症、损伤严重程度、损伤模式、入院生命体征和并发症。排列重要性方法确定了院内并发症的主要预测因素。

结果

在321,355例肋骨骨折患者中,183,303例(57.0%)为孤立性肋骨骨折。所有肋骨骨折患者并发症的五个主要预测因素是年龄、入院时的格拉斯哥昏迷量表(GCS)、修订心脏风险指数(RCRI)、慢性阻塞性肺疾病(COPD)和酒精使用障碍。对于孤立性肋骨骨折患者,同样的预测因素适用,但顺序为:年龄、RCRI、GCS、COPD和酒精使用障碍。使用这些预测因素的逻辑回归模型显示,在整个队列中对并发症具有可接受的判别能力[AUC(95%CI):0.72(0.71 - 0.72)],在孤立性肋骨骨折患者中也具有可接受的判别能力[AUC(95%CI):0.72(0.71 - 0.73)]。

结论

心血管风险、年龄和入院时的意识水平是保守治疗的肋骨骨折患者并发症的关键预测因素。尽管总体并发症发生率仍然较低,但具有多种心血管危险因素的老年患者面临病情恶化的风险更高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9de/12041140/02b5c423785e/68_2025_2860_Fig1_HTML.jpg

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