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社论：药物对小儿强迫症纹状体静息状态连接的影响：调节神经发育轨迹的机会？

Editorial: Pharmacological Effects on Striatal Resting-State Connectivity in Pediatric Obsessive-Compulsive Disorder: An Opportunity to Modulate Neurodevelopmental Trajectories?

机构信息

Child and Adolescent Mental Health Research Group, Institut de Recerca Sant Joan de Déu, Barcelona, Spain, the Hospital Sant Joan de Déu, Barcelona, Spain, and the CIBERSAM, Instituto de Salud Carlos III, Madrid, Spain.

出版信息

J Am Acad Child Adolesc Psychiatry. 2019 May;58(5):478-480. doi: 10.1016/j.jaac.2018.09.426. Epub 2019 Feb 22.

DOI:10.1016/j.jaac.2018.09.426
PMID:30799068
Abstract

The cortico-striato-thalamo-cortical (CSTC) circuit has been traditionally implicated in the underlying neural pathophysiology of obsessive-compulsive disorder (OCD). The CSTC involves parallel, partly segregated, but intrinsically communicating circuits involved in motor, cognitive, affective, and motivational processes..

摘要

皮质纹状体丘脑皮质（CSTC）回路传统上被认为与强迫症（OCD）的潜在神经病理生理学有关。CSTC 涉及参与运动、认知、情感和动机过程的平行、部分隔离但本质上相互沟通的回路。

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