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一万例连续胃癌胃切除术:一位外科大师的观点

Ten Thousand Consecutive Gastrectomies for Gastric Cancer: Perspectives of a Master Surgeon.

作者信息

Choi Yoon Young, Cho Minah, Kwon In Gyu, Son Taeil, Kim Hyoung Il, Choi Seung Ho, Cheong Jae Ho, Hyung Woo Jin

机构信息

Department of Surgery, Yonsei University Health System, Yonsei University College of Medicine, Seoul, Korea.

出版信息

Yonsei Med J. 2019 Mar;60(3):235-242. doi: 10.3349/ymj.2019.60.3.235.

Abstract

As radical gastrectomy with lymph node dissection is currently the best strategy to cure gastric cancer, the role of the surgeon remains quite important in conquering it. Dr. Sung Hoon Noh, a surgeon and surgical oncologist specializing in gastric cancer, has treated gastric cancer for 30 years and has conducted over 10000 cases of gastrectomy for gastric cancer. He first adapted an electrocautery device into gastric cancer surgery and has led standardization of surgical procedures, including spleen preserving gastrectomy. His procedures based on patient-oriented insights have become the basis of the concept of enhanced recovery after surgery. He has also contributed to improving patient's survival through adoption of a multidisciplinary approach: he proved the benefit of adjuvant chemotherapy after radical D2 gastrectomy for stage II/III gastric cancer in clinical trials, updating treatment guidelines throughout the world. Dr. Noh also opened the era of precision medicine for treating gastric cancer, as he developed and validated a mRNA expression based algorithm to predict prognosis and response to chemotherapy. This article reviews his contribution and long history of service in the field of gastric cancer. The perspectives of this master surgeon, based on his profound experience and insights, will outline directions for integrative multidisciplinary health care and how can surgeons prepare for the future.

摘要

由于根治性胃切除术加淋巴结清扫术目前是治愈胃癌的最佳策略,外科医生在攻克胃癌方面的作用仍然相当重要。Sung Hoon Noh博士是一位专门从事胃癌治疗的外科医生和外科肿瘤学家,他治疗胃癌已有30年,进行了超过10000例胃癌胃切除术。他首先将电灼设备应用于胃癌手术,并主导了包括保留脾脏胃切除术在内的手术程序标准化。他基于以患者为导向的见解所开展的手术已成为术后加速康复概念的基础。他还通过采用多学科方法为提高患者生存率做出了贡献:他在临床试验中证明了II/III期胃癌根治性D2胃切除术后辅助化疗的益处,更新了全球的治疗指南。Noh博士还开创了胃癌精准医疗的时代,他开发并验证了一种基于mRNA表达的算法来预测预后和化疗反应。本文回顾了他在胃癌领域的贡献和悠久的服务历史。这位主刀医生基于其丰富经验和深刻见解的观点,将概述综合多学科医疗保健的方向以及外科医生如何为未来做好准备。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca6a/6391520/ab63f0ab55e9/ymj-60-235-g001.jpg

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