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2005年至2015年韩国前列腺癌患病率和根治性前列腺切除术率随年龄的变化趋势及结构变化

Trends in Prostate Cancer Prevalence and Radical Prostatectomy Rate according to Age Structural Changes in South Korea between 2005 and 2015.

作者信息

Lee Hyun Young, Park Suyeon, Doo Seung Whan, Yang Won Jae, Song Yun Seob, Kim Jae Heon

机构信息

Department of Urology, Soonchunhyang University Seoul Hospital, Soonchunhyang University Medical College, Seoul, Korea.

Department of Biostatistics, Soonchunhyang University Seoul Hospital, Seoul, Korea.

出版信息

Yonsei Med J. 2019 Mar;60(3):257-266. doi: 10.3349/ymj.2019.60.3.257.

DOI:10.3349/ymj.2019.60.3.257
PMID:30799588
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6391527/
Abstract

PURPOSE

Radical prostatectomy (RP) is one of main treatments for prostate cancer (Pca). The prevalence of Pca has been decreasing in recent reports. However, no study has reported trends in Pca prevalence or RP rate according to age structural changes. The objective of this study was to investigate trends in Pca prevalence and frequency of RP according to age structural change.

MATERIALS AND METHODS

We evaluated trends in Pca prevalence and RP rate using National Health Insurance Data from 2005 to 2015. Relationships for Pca prevalence and RP rate with age structural change were also determined. Primary outcomes included trends in Pca prevalence and RP rates according to age groups, comparing those before and after 2011.

RESULTS

Pca prevalence tended to increase before 2011 and decreased after 2011 in persons in the 60-years age group. RP rate increased pattern before 2011 and decreased after 2011 in age groups of 50s, 60s, and over 70s. Pca prevalence and age structural change showed a significantly positive relationship in all age groups, except for the age group under 40 years. RP rate and age structural change also showed a significantly positive relationship in all age groups.

CONCLUSION

Age structural change can affect the decreasing trend in Pca prevalence and RP rate in South Korea. Future studies are needed to validate this result.

摘要

目的

根治性前列腺切除术(RP)是前列腺癌(Pca)的主要治疗方法之一。近期报告显示Pca的患病率一直在下降。然而,尚无研究报道根据年龄结构变化的Pca患病率或RP率趋势。本研究的目的是调查根据年龄结构变化的Pca患病率和RP频率趋势。

材料与方法

我们使用2005年至2015年的国民健康保险数据评估了Pca患病率和RP率的趋势。还确定了Pca患病率和RP率与年龄结构变化的关系。主要结果包括按年龄组划分的Pca患病率和RP率趋势,比较2011年前后的情况。

结果

60岁年龄组人群中,Pca患病率在2011年前呈上升趋势,2011年后下降。50多岁、60多岁和70岁以上年龄组的RP率在2011年前呈上升趋势,2011年后下降。除40岁以下年龄组外,所有年龄组的Pca患病率与年龄结构变化均呈显著正相关。RP率与年龄结构变化在所有年龄组中也呈显著正相关。

结论

年龄结构变化会影响韩国Pca患病率和RP率的下降趋势。需要进一步的研究来验证这一结果。

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本文引用的文献

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Impact of Early Salvage Androgen Deprivation Therapy in Localized Prostate Cancer after Radical Prostatectomy: A Propensity Score Matched Analysis.早期挽救性雄激素剥夺疗法对前列腺癌根治术后局限性前列腺癌的影响:一项倾向评分匹配分析
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2010 - 2015年美国前列腺癌治疗趋势
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Avicenna J Med. 2020 Jul 3;10(3):93-101. doi: 10.4103/ajm.ajm_19_20. eCollection 2020 Jul-Sep.
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