Department of Urology, Asan Medical Center, Ulsan University College of Medicine, Seoul, Korea.
Department of Urology, Chonbuk National University Medical School, Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, Korea.
Investig Clin Urol. 2017 Nov;58(6):434-439. doi: 10.4111/icu.2017.58.6.434. Epub 2017 Oct 25.
Despite the necessity, to date, no detailed database of prostate cancer, especially one that includes clinicopathological data, has been created in Korea. For that reason, the Korean Urological Oncology Society (KUOS) decided to create the Korean Prostate Cancer Database (KPCD).
The KPCD program was introduced in 2010. After considering regional distribution, a total of 20 hospitals participated in the KPCD. The Database consists of 4 domains (demographic, pretreatment, treatment, and follow-up data) and 135 variables.
In total, 7,608 men with prostate cancer between 2000 and 2010 were registered in the KPCD. The mean age at the time of diagnosis was 67.6±7.7 years. The mean PSA at diagnosis was 74.0±366.9 ng/mL, and the proportions of patients with Gleason scores of ≤6, 7, and 8-10 were 37.0%, 26.7%, and 34.2%, respectively. At diagnosis, 62.3% of the patients had localized tumors, 14.6% had regional, 12.8% had distant, and 10.4% cases were from unknown diseases. With regards to the initial treatment modality employed, 1.3% of patients were managed with active surveillance, 62.1% underwent surgery, 4.3% underwent radiotherapy, 27.1% had androgen deprivation therapy, and 5.2% underwent unknown therapies. The 5-year cancer-specific survival rate of patients in the KPCD was 98.6% in the localized stage, 94.8% in the regional stage, 74.7% in the distant stage, and 86.9% in the unknown stage.
The KUOS created a relatively successful database of patients with prostate cancer in Korea. The KPCD will continue to improve the availability of data regarding prostate cancer.
尽管有必要，但迄今为止，韩国尚未建立详细的前列腺癌数据库，特别是包含临床病理数据的数据库。为此，韩国泌尿肿瘤学会（KUOS）决定创建韩国前列腺癌数据库（KPCD）。
KPCD 项目于 2010 年启动。在考虑区域分布后，共有 20 家医院参与了 KPCD。该数据库由 4 个领域（人口统计学、治疗前、治疗和随访数据）和 135 个变量组成。
KPCD 共登记了 2000 年至 2010 年期间的 7608 名前列腺癌男性患者。诊断时的平均年龄为 67.6±7.7 岁。诊断时的平均 PSA 为 74.0±366.9ng/ml，Gleason 评分≤6、7 和 8-10 的患者比例分别为 37.0%、26.7%和 34.2%。诊断时，62.3%的患者肿瘤局限，14.6%的患者区域转移，12.8%的患者远处转移，10.4%的患者疾病不明。在初始治疗方式上，1.3%的患者采用主动监测，62.1%的患者采用手术治疗，4.3%的患者采用放疗，27.1%的患者采用雄激素剥夺治疗，5.2%的患者采用不明治疗方法。KPCD 中局限性、区域性、远处转移和未知期前列腺癌患者的 5 年癌症特异性生存率分别为 98.6%、94.8%、74.7%和 86.9%。
KUOS 在韩国成功创建了前列腺癌患者数据库。KPCD 将继续提高前列腺癌数据的可用性。
