College of Food Science and Engineering, Northwest A & F University, Yangling, Shaanxi, P.R. China.
State Key Laboratory of Food Science & Technology, Jiangnan University, Wuxi, Jiangsu, P.R. China.
Crit Rev Food Sci Nutr. 2020;60(4):541-555. doi: 10.1080/10408398.2018.1544883. Epub 2019 Feb 23.
Polyphenols, as one group of secondary metabolite, are widely distributed in plants and have been reported to show various bioactivities in recent year. Starch digestion not only is related with food industrial applications such as brewing but also plays an important role in postprandial blood glucose level, and therefore insulin resistance. Many studies have shown that dietary phenolic extracts and pure polyphenols can retard starch digestion , and the retarding effect depends on the phenolic composition and molecular structure. Besides, dietary polyphenols have also been reported to alleviate elevation of blood glucose level after meal, indicating the inhibition of starch digestion . This review aims to analyze how dietary polyphenols affect starch digestion both and . We can conclude that the retarded starch digestion by polyphenols results from inhibition of key digestive enzymes, including α-amylase and α-glucosidase, as well as from interactions between polyphenols and starch. The alleviation of postprandial hyperglycemia by polyphenols might be caused by both the inhibited starch digestion and the influenced glucose transport. Therefore, phenolic extracts or pure polyphenols may be alternatives for preventing and treating type II diabetes disease.
多酚作为一类次生代谢产物,广泛分布于植物中,近年来已被报道具有多种生物活性。淀粉消化不仅与酿造等食品工业应用有关,而且在餐后血糖水平和胰岛素抵抗方面也起着重要作用。许多研究表明,膳食酚提取物和纯多酚可以延缓淀粉消化,这种延缓作用取决于酚类成分和分子结构。此外,膳食多酚也被报道可以减轻餐后血糖升高,表明对淀粉消化的抑制。本文旨在分析膳食多酚如何影响淀粉消化。我们可以得出结论,多酚通过抑制关键消化酶(包括α-淀粉酶和α-葡萄糖苷酶)以及多酚与淀粉之间的相互作用来延缓淀粉消化。多酚缓解餐后高血糖可能是由于抑制淀粉消化和影响葡萄糖转运。因此,酚类提取物或纯多酚可能是预防和治疗 II 型糖尿病的替代方法。