Ocaña Juan, Peromingo Roberto, Nuño Javier
General and Digestive Surgery Department, University Hospital Ramón y Cajal, Madrid 28043, Spain.
J Surg Case Rep. 2019 Feb 19;2019(2):rjz041. doi: 10.1093/jscr/rjz041. eCollection 2019 Feb.
Sinonasal undifferentiated carcinoma (SNUC) is a rare tumor with poor prognosis and high incidence of distant metastasis, even when a good loco-regional control is achieved.
We report the case of a 43-year-old female with SNUC diagnosis. Craniofacial resection with orbital exenteration and radiotherapy in tumor bed and lymph node chain was performed. After 10 months, SNUC hepatic relapse (sIII and sVIII) is diagnosed. We administered chemotherapy and then, surgical resection was carried out. After surgery, two new relapses were diagnosed, at 9 and 21 months where surgical management was performed in both cases. 56 months after SNUC diagnosis, the patient has no evidence of recurrence.
Recommended oncological clinical guidelines for distant metastases in SNUC are chemotherapy. Surgical management in oligometastatic disease in SNUC should be considered.
鼻窦未分化癌（SNUC）是一种罕见肿瘤，预后较差，远处转移发生率高，即便实现了良好的局部区域控制亦是如此。
我们报告一例43岁诊断为SNUC的女性患者。实施了颅面切除联合眶内容摘除术，并对瘤床和淋巴结链进行放疗。10个月后，诊断为SNUC肝转移（sIII和sVIII）。我们给予化疗，随后进行手术切除。术后，又诊断出两次复发，分别在9个月和21个月，这两例均进行了手术处理。SNUC诊断56个月后，患者无复发迹象。
SNUC远处转移推荐的肿瘤学临床指南是化疗。对于SNUC寡转移疾病应考虑手术处理。
