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来自印度的两株广泛耐药结核分枝杆菌分离株的全基因组测序

Whole-Genome Sequencing of Two Extensively Drug-Resistant Mycobacterium tuberculosis Isolates from India.

作者信息

Rufai Syed Beenish, Singh Sarman

机构信息

Division of Clinical Microbiology and Molecular Medicine, All India Institute of Medical Sciences, New Delhi, India.

Clinical Microbiology and Molecular Medicine, All India Institute of Medical Sciences, Bhopal, India.

出版信息

Microbiol Resour Announc. 2019 Feb 14;8(7). doi: 10.1128/MRA.00007-19. eCollection 2019 Feb.

Abstract

The emergence of extensively drug-resistant tuberculosis (XDR-TB) presents a considerable challenge and a public health concern due to the high mortality rate of this disease. Whole-genome sequencing (WGS) of XDR-TB isolates is thus essential for understanding the mechanism of drug resistance. Here we report whole-genome sequences of two XDR-TB strains of two lineages from India.

摘要

广泛耐药结核病(XDR-TB)的出现带来了巨大挑战,因其高死亡率而成为公共卫生问题。因此,对XDR-TB分离株进行全基因组测序对于了解耐药机制至关重要。在此,我们报告了来自印度的两个谱系的两株XDR-TB菌株的全基因组序列。

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