Obstet Gynecol. 2019 Mar;133(3):e238-e248. doi: 10.1097/AOG.0000000000003126.
Morcellation is a surgical technique used to reduce the size of the uterus or myomas by creating smaller pieces to allow the tissue to be removed through small incisions or with laparoscopic instruments. Open (uncontained) morcellation of the uterus and myomas has been scrutinized because of the possible spread of an unsuspected leiomyosarcoma while using a power morcellator during a hysterectomy or myomectomy for presumed symptomatic uterine leiomyomas. Before considering open morcellation of the uterus, a woman should be evaluated to determine if she is at increased risk of malignancy of the uterine corpus. Morcellation of a malignancy is contraindicated, and women should be evaluated preoperatively to identify malignancy. However, leiomyosarcoma cannot be reliably diagnosed preoperatively; thus, there is a risk that a woman with a presumed leiomyoma may have a malignancy that may be spread through morcellation, leading to a potentially worsened prognosis. Although an abdominal hysterectomy or myomectomy may reduce the chance of spreading cancer cells in women with undiagnosed leiomyosarcoma, it is associated with increased morbidity when compared with minimally invasive approaches. The obstetrician-gynecologist and patient should engage in shared decision making, including informed consent explaining the risks and benefits of each approach to surgery for presumed leiomyomas, the risks and benefits of morcellation, and alternatives to morcellation.
子宫组织切碎术是一种通过创建更小的碎片来减少子宫或肌瘤大小的手术技术,以便通过小切口或腹腔镜器械将组织切除。由于在子宫切除术或肌瘤切除术期间使用电动组织切碎器时可能会无意中传播未被怀疑的平滑肌肉瘤,因此对开放性(未包含)子宫和肌瘤组织切碎术进行了仔细审查。在考虑开放性子宫组织切碎术之前,应评估女性是否存在子宫体恶性肿瘤的风险增加。恶性肿瘤的切碎术是禁忌的,应在术前对女性进行评估以确定恶性肿瘤。然而,平滑肌肉瘤不能可靠地术前诊断;因此,患有假定的平滑肌瘤的女性可能患有恶性肿瘤,这些肿瘤可能通过切碎术传播,从而导致预后可能恶化。虽然腹式子宫切除术或肌瘤切除术可能会降低患有未确诊平滑肌肉瘤的女性癌症细胞扩散的机会,但与微创手术方法相比,它与更高的发病率相关。妇产科医生和患者应进行共同决策,包括知情同意,解释每种假定平滑肌瘤手术方法的风险和益处、切碎术的风险和益处,以及替代切碎术的方法。