Obstet Gynecol. 2021 Mar 1;137(3):e63-e74. doi: 10.1097/AOG.0000000000004291.
Morcellation is a surgical technique used to reduce the size of the uterus or myomas by creating smaller pieces to allow the tissue to be removed through small incisions or with laparoscopic instruments. Open (uncontained) morcellation of the uterus and myomas has been scrutinized because of the possible spread of an unsuspected leiomyosarcoma while using a power morcellator during a hysterectomy or myomectomy for presumed symptomatic uterine leiomyomas. Before considering morcellation of the uterus, a woman should be evaluated to determine if she is at increased risk of malignancy of the uterine corpus. Morcellation of a malignancy is contraindicated and women should be evaluated preoperatively to identify malignancy. However, leiomyosarcoma cannot be reliably diagnosed preoperatively; thus, there is a risk that a woman with a presumed leiomyoma may have a malignancy that may be spread through morcellation, leading to a potentially worsened prognosis. Although an abdominal hysterectomy or myomectomy may reduce the chance of spreading cancer cells in women with undiagnosed leiomyosarcoma, it is associated with increased morbidity when compared with minimally invasive approaches. The obstetrician-gynecologist and patient should engage in shared decision making, including informed consent, explaining the risks and benefits of each approach to surgery for presumed leiomyomas, the risks and benefits of morcellation, and alternatives to morcellation.
子宫组织切碎术是一种通过将子宫或肌瘤切成较小的碎片以通过小切口或腹腔镜器械进行切除来减小子宫或肌瘤大小的手术技术。由于在进行子宫切除术或子宫肌瘤剔除术时使用电动组织切碎器可能会传播未被怀疑的平滑肌肉瘤,因此对开放性(无包裹)子宫和肌瘤组织切碎术进行了仔细审查。在考虑对子宫进行切碎术之前,应评估女性是否存在子宫体恶性肿瘤的风险增加。恶性肿瘤的切碎术是禁忌的,并且应该在术前对女性进行评估以确定恶性肿瘤。但是,平滑肌肉瘤不能可靠地术前诊断;因此,患有假定的平滑肌瘤的女性可能存在可能通过切碎术传播的恶性肿瘤,这可能导致预后恶化。尽管腹式子宫切除术或子宫肌瘤剔除术可能会降低患有未诊断的平滑肌肉瘤的女性传播癌细胞的机会,但与微创方法相比,它会增加发病率。妇产科医生和患者应共同做出决策,包括知情同意,解释每种手术方法治疗假定的平滑肌瘤的风险和益处,切碎术的风险和益处,以及切碎术的替代方法。