Hu E, Levine J
Cancer. 1986 Mar 15;57(6):1101-4. doi: 10.1002/1097-0142(19860315)57:6<1101::aid-cncr2820570606>3.0.co;2-a.
The authors report the case of a patient with malignant thymoma unresponsive to combination chemotherapy (cyclophosphamide, doxorubicin, vincristine, and prednisone [CHOP] and cisplatin/VP-16) who subsequently achieved clinical response to continuous daily prednisone. A review of the literature indicates that prednisone and cisplatin are the most active agents in the treatment of malignant thymoma.
作者报告了一例恶性胸腺瘤患者,其对联合化疗(环磷酰胺、阿霉素、长春新碱和泼尼松[CHOP]以及顺铂/依托泊苷)无反应,但随后对每日持续使用泼尼松产生了临床反应。文献回顾表明,泼尼松和顺铂是治疗恶性胸腺瘤最有效的药物。