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美国外科医师学会手术风险计算器预测老年妇科肿瘤患者行剖腹术的处置能力。

The American College of Surgeon's surgical risk calculator's ability to predict disposition in older gynecologic oncology patients undergoing laparotomy.

机构信息

Department of Obstetrics, Gynecology and Women's Health, University of Minnesota, Minneapolis, MN, United States of America.

Department of Obstetrics, Gynecology and Women's Health, University of Minnesota, Minneapolis, MN, United States of America.

出版信息

J Geriatr Oncol. 2019 Jul;10(4):618-622. doi: 10.1016/j.jgo.2019.02.008. Epub 2019 Feb 23.

Abstract

OBJECTIVES

The American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) surgical risk calculator calculates risk of postoperative complications utilizing clinically apparent preoperative variables. If validated for patients with gynecologic cancers, this can be an effective tool in to use for shared decision-making, especially in the older (70+ years of age) patient population for whom surgical risks and potential loss of independence is increased. The primary objective of this study was to evaluate the ability of the ACS NSQIP surgical risk calculator to predict discharge to a post-acute care among older (age 70+ years) gynecologic oncology patients undergoing laparotomy. The secondary objectives were to assess its ability to predict postoperative complications and death.

METHODS

This was a retrospective cohort study of gynecologic oncology patients 70+ years of age undergoing laparotomy. Surgical procedures, 21 preoperative variables, postoperative complications, and patient disposition were abstracted from the medical record. Risk scores for seven postoperative complications and discharge to post-acute care were calculated. The association between risk scores and outcomes were assessed using logistic regression and predictive ability was evaluated using the c-statistic and Brier score.

RESULTS

204 surgeries were performed on 200 patients between January 1, 2009 and December 31, 2013. The mean age was 76.3 ± 5.1 years; 87% were independent at baseline. A total of 79 (41%) were discharged to post-acute care. The calculator's ability to predict discharge to post-acute care was reasonable (c- statistic =0.708, Brier = 0.205). Although the calculator did not accurately predict all postoperative complications, the calculator's ability to predict death was strong (c-statistic = 0.811, Brier = 0.015).

CONCLUSION

For older patients with an elevated calculated risk of discharge to post acute care the possibility of discharge to post-acute care should be discussed preoperatively. For patients with a higher risk of death, non-surgical management options should be considered when available.

摘要

目的

美国外科医师学会国家外科质量改进计划(ACS NSQIP)手术风险计算器利用临床明显的术前变量来计算术后并发症的风险。如果该方法在妇科癌症患者中得到验证,那么它可以成为用于共同决策的有效工具,特别是对于手术风险和潜在丧失独立性增加的老年(70 岁以上)患者人群。本研究的主要目的是评估 ACS NSQIP 手术风险计算器预测接受剖腹术的老年(年龄 70 岁以上)妇科肿瘤患者转至急性后护理的能力。次要目标是评估其预测术后并发症和死亡的能力。

方法

这是一项回顾性队列研究,纳入了 70 岁以上接受剖腹术的妇科肿瘤患者。从病历中提取手术程序、21 个术前变量、术后并发症和患者转归。计算了 7 种术后并发症和转至急性后护理的风险评分。使用逻辑回归评估风险评分与结局之间的关联,并使用 C 统计量和 Brier 评分评估预测能力。

结果

2009 年 1 月 1 日至 2013 年 12 月 31 日期间,共进行了 204 例手术,共涉及 200 名患者。平均年龄为 76.3±5.1 岁,基线时 87%的患者为独立生活。共有 79 例(41%)患者转至急性后护理机构。计算器预测转至急性后护理的能力尚可(C 统计量=0.708,Brier=0.205)。尽管计算器不能准确预测所有术后并发症,但计算器预测死亡的能力较强(C 统计量=0.811,Brier=0.015)。

结论

对于预计术后转至急性后护理机构风险较高的老年患者,应在术前讨论转至急性后护理机构的可能性。对于死亡风险较高的患者,在有条件的情况下应考虑非手术治疗方案。

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Evaluation of the performance of the ACS NSQIP surgical risk calculator in gynecologic oncology patients undergoing laparotomy.
Gynecol Oncol. 2016 May;141(2):281-286. doi: 10.1016/j.ygyno.2016.02.015. Epub 2016 Feb 24.

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