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尼日利亚夸拉州沙眼的患病率及危险因素:全球沙眼地图绘制项目八项基于人群调查的结果

Prevalence of and risk factors for trachoma in Kwara state, Nigeria: Results of eight population-based surveys from the Global Trachoma Mapping Project.

作者信息

Alada Joel J, Mpyet Caleb, Florea Victor V, Boisson Sophie, Willis Rebecca, Muhammad Nasiru, Bakhtiari Ana, Adamu Mohammed D, Pavluck Alexandre L, Umar Murtala M, Isiyaku Sunday, William Adamani, Oyinloye Funso Olu Peter, Olobio Nicholas, Solomon Anthony W

机构信息

a Department of Ophthalmology , Federal Medical Centre , Makurdi , Nigeria.

b Department of Ophthalmology , University of Jos , Jos , Nigeria.

出版信息

Ophthalmic Epidemiol. 2018 Dec;25(sup1):53-61. doi: 10.1080/09286586.2018.1437188.

Abstract

PURPOSE

To determine the prevalence of and risk factors for trachoma in selected local government areas (LGAs) of Kwara State, Nigeria.

METHODOLOGY

Population-based cross-sectional surveys were conducted in eight LGAs of Kwara State using Global Trachoma Mapping Project (GTMP) protocols. In each LGA, 25 villages were selected using probability-proportional-to-size sampling; 25 households were selected from each village using compact segment sampling. All residents of selected households aged ≥1 year were examined by GTMP-certified graders for trachomatous inflammation-follicular (TF) and trichiasis using the simplified trachoma grading scheme. Water, sanitation, and hygiene (WASH) data were also collected.

RESULTS

A total of 28,506 residents were enumerated in 4769 households across the eight LGAs. TF prevalence in children aged 1-9 years ranged from 0.2% (95% CI 0.0-0.3%) to 1.3% (95% CI 0.7-2.1%), while trichiasis prevalence in persons ≥15 years was <0.2% in each LGA. Access to improved water source was the lowest in Edu (62%), while access to improved sanitation facilities was the lowest in Asa (6%) and the highest in Ilorin East (64%). Children aged 1-4 years had 0.63 (95% CI 0.40-0.99) times lower odds of having TF compared to children aged 5-9 years. Children in households with ≥5 resident 1-9-year-old children had 1.63 (95% CI 1.02-2.60) times greater odds of having TF compared to those in households with <5 resident children.

CONCLUSION

Trachoma is not a public health problem in Kwara State. Provision of adequate water and sanitation services should be a priority here, as a foundation for the health of the population.

摘要

目的

确定尼日利亚夸拉州部分地方政府辖区(LGAs)沙眼的患病率及危险因素。

方法

采用全球沙眼地图绘制项目(GTMP)方案,在夸拉州的8个地方政府辖区开展基于人群的横断面调查。在每个地方政府辖区,采用规模比例概率抽样法选取25个村庄;从每个村庄中采用紧凑分段抽样法选取25户家庭。使用简化沙眼分级方案,由GTMP认证的分级人员对所选家庭中年龄≥1岁的所有居民进行沙眼滤泡性炎症(TF)和倒睫检查。同时收集水、环境卫生和个人卫生(WASH)数据。

结果

在8个地方政府辖区的4769户家庭中,共统计了28506名居民。1 - 9岁儿童的TF患病率在0.2%(95%可信区间0.0 - 0.3%)至1.3%(95%可信区间0.7 - 2.1%)之间,而每个地方政府辖区中15岁及以上人群的倒睫患病率均<0.2%。埃杜地区获得改善水源的比例最低(62%),而阿萨地区获得改善卫生设施的比例最低(6%),伊洛林东区最高(64%)。与5 - 9岁儿童相比,1 - 4岁儿童患TF的几率低0.63倍(95%可信区间0.40 - 0.99)。与家中居住1 - 9岁儿童少于5名的家庭相比,家中居住5名及以上1 - 9岁儿童的家庭中儿童患TF的几率高1.63倍(95%可信区间1.02 - 2.60)。

结论

沙眼在夸拉州不是一个公共卫生问题。提供充足的水和卫生服务应成为该地区的优先事项,作为民众健康的基础。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fcd/6444274/1e5a8abec17b/IOPE_A_1437188_F0001_OC.jpg

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