Malyarenko Timofey V, Kicha Alla A, Ivanchinia Natalia V, Kalinovsky Anatoly I, Dmitrenok Pavel S, Stonik Valentin A
Nat Prod Commun. 2016 Sep;11(9):1251-1252.
Two polar steroid compounds, taurochenodeoxycholic acid sodium salt (1) and a rare cyclic steroid glycoside luzonicoside A (2), were isolated from the tropical starfish Leiaster sp. and identified by extensive NMR and ESIMS techniques. The isolation of primary bile acid 1 is the first report from a representative of the class Asteroidea and on the whole in invertebrates. Its presence confirms the hypothesis about the digestive role of some polar steroids in starfish and possibly demonstrates the parallel evolution of fat emulsifying agents in vertebrates and some starfish. Compound 2 was also obtained from starfish belonging to this genus for the first time. This finding indicates that cyclic steroid glycosides are more widely distributed in starfish than the two species of the genus Echinaster from which they were isolated earlier.
从热带海星Leiaster sp.中分离出两种极性甾体化合物，牛磺鹅去氧胆酸钠盐（1）和一种罕见的环状甾体糖苷luzonicoside A（2），并通过广泛的核磁共振（NMR）和电喷雾电离质谱（ESIMS）技术进行了鉴定。初级胆汁酸1的分离是来自海星纲代表以及整个无脊椎动物的首次报道。它的存在证实了关于某些极性甾体在海星中消化作用的假说，并可能证明了脊椎动物和某些海星中脂肪乳化剂的平行进化。化合物2也是首次从该属海星中获得。这一发现表明，环状甾体糖苷在海星中的分布比之前从中分离出它们的棘冠海星属的两个物种更为广泛。
