Weinbaum P J, Cassidy S B, Vintzileos A M, Campbell W A, Ciarleglio L, Nochimson D J
Obstet Gynecol. 1986 Mar;67(3 Suppl):31S-33S. doi: 10.1097/00006250-198603001-00009.
Fetal exposure to valproic acid has recently been associated with an increased incidence of neural tube defects. The prenatal detection of a fetus with both hydrocephalus and meningomyelocele after valproic acid exposure is presented and specific recommendations made for antepartum evaluation in future pregnancies.
胎儿暴露于丙戊酸最近被认为与神经管缺陷的发生率增加有关。本文介绍了丙戊酸暴露后产前检测出患有脑积水和脊髓脊膜膨出的胎儿,并针对未来妊娠的产前评估提出了具体建议。