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顶端脱垂修复术后短暂性排尿功能障碍围手术期危险因素的回顾性队列研究

Retrospective Cohort Study on the Perioperative Risk Factors for Transient Voiding Dysfunction After Apical Prolapse Repair.

作者信息

Eto Chidimma, Ford Alexcis T, Smith Madeline, Advolodkina Polina, Northington Gina M

机构信息

From the Emory University School of Medicine, Atlanta, GA.

出版信息

Female Pelvic Med Reconstr Surg. 2019 Mar/Apr;25(2):167-171. doi: 10.1097/SPV.0000000000000675.

Abstract

OBJECTIVES

The primary aim was to compare the incidence of transient voiding dysfunction (TVD) between vaginal uterosacral ligament suspension, sacrospinous ligament fixation, and robotic sacrocolpopexy. Secondarily, we identified risk factors for TVD and associated postoperative complications.

METHODS

This was a retrospective cohort study of women who underwent apical repair at 1 institution. Data were collected from electronic medical records and were presented as means (SD) or numbers (percent) as appropriate. Univariate and multivariate analyses were performed to identify risk factors for TVD and its associated postoperative complications.

RESULTS

Three hundred sixty women were included in analysis. Two hundred nineteen (60.8%) passed their voiding trial and 141 (39.2%) experienced TVD. The TVD group demonstrated a higher age, age-adjusted Charlson Comorbidity Index score, and preoperative postvoid residual (all P < 0.05). Univariate analysis demonstrated higher rates of TVD in the vaginal uterosacral ligament suspension and sacrospinous ligament fixation groups compared with the robotic sacrocolpopexy group (P = 0.012). Transient voiding dysfunction occurred more frequently with a concomitant anti-incontinence procedure, anterior repair, and/or posterior repair (all P < 0.05). In multivariate analysis, only an anti-incontinence procedure and concomitant anterior repair were independently associated with a risk of TVD (odds ratio [OR], 2.23; 95% confidence interval [CI], 1.37-3.62, and OR, 2.20; CI, 1.14-4.27, respectively). Transient voiding dysfunction was associated with a culture-proven urinary tract infection within 6 weeks (OR, 3.2; CI, 1.3-8.55).

CONCLUSIONS

There was no difference in TVD between types of apical repair. Concomitant anti-incontinence procedure and anterior repair were associated with TVD. Women with TVD have an increased risk of postoperative urinary tract infections.

摘要

目的

主要目的是比较阴道骶子宫韧带悬吊术、骶棘韧带固定术和机器人辅助骶骨阴道固定术之间短暂性排尿功能障碍(TVD)的发生率。其次,我们确定了TVD的危险因素及相关术后并发症。

方法

这是一项对在1家机构接受顶端修复的女性进行的回顾性队列研究。数据从电子病历中收集,并根据情况以均值(标准差)或数量(百分比)呈现。进行单因素和多因素分析以确定TVD及其相关术后并发症的危险因素。

结果

360名女性纳入分析。219名(60.8%)通过排尿试验,141名(39.2%)出现TVD。TVD组年龄更大、年龄调整后的Charlson合并症指数评分更高且术前排尿后残余尿量更多(均P<0.05)。单因素分析显示,与机器人辅助骶骨阴道固定术组相比,阴道骶子宫韧带悬吊术和骶棘韧带固定术组的TVD发生率更高(P=0.012)。伴随抗尿失禁手术、前路修复和/或后路修复时,短暂性排尿功能障碍更常发生(均P<0.05)。在多因素分析中,只有抗尿失禁手术和伴随的前路修复与TVD风险独立相关(优势比[OR]分别为2.23;95%置信区间[CI]为1.37 - 3.62,以及OR为2.20;CI为1.14 - 4.27)。短暂性排尿功能障碍与6周内经培养证实的尿路感染相关(OR为3.2;CI为1.3 - 8.55)。结论:顶端修复类型之间的TVD无差异。伴随抗尿失禁手术和前路修复与TVD相关。发生TVD的女性术后尿路感染风险增加。

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