Sorbonne Université, Inserm, Unité "Réhabilitation chirurgicale mini-invasive et robotisée de l'audition", Paris, France.
AP-HP, GHU Pitié-Salpêtrière, Service ORL, Otologie, implants auditifs et chirurgie de la base du crâne, Paris, France.
PLoS One. 2019 Feb 26;14(2):e0212855. doi: 10.1371/journal.pone.0212855. eCollection 2019.
This study proposes a practical model for a new approach to the posterior fossa in common domestic pigs. Several surgical procedures can be simulated in the nonliving pig model, including soft tissue dissection, drilling of temporal bone, dural incision, access to the cerebellopontine angle, exposure of cranial nerves and drilling of the internal auditory canal. The pig model perfectly simulates standard otological and neurosurgical procedures, and we highlight the feasibility of our approach for further experiments in a living pig model with the possibility of reproducing the model for research on cranial nerves in pigs to study their electrophysiological behavior.
本研究提出了一种在常见家猪的后颅窝中应用新方法的实用模型。该非活体猪模型可模拟多种手术操作，包括软组织解剖、颞骨钻孔、硬脑膜切开、到达桥小脑角、颅神经显露和内听道钻孔。猪模型完美模拟了标准耳科学和神经外科学手术，我们强调了我们的方法在活体猪模型中进行进一步实验的可行性，并且有可能为猪颅神经的研究复制模型，以研究其电生理行为。
