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一项关于社会认知缺陷对重性抑郁障碍患者心理社会功能影响的系统评价及治疗干预机会。

A systematic review of the impact of social cognitive deficits on psychosocial functioning in major depressive disorder and opportunities for therapeutic intervention.

机构信息

Discipline of Psychiatry, Adelaide Medical School, The University of Adelaide, Adelaide, South Australia 5005, Australia.

Discipline of Psychiatry, Adelaide Medical School, The University of Adelaide, Adelaide, South Australia 5005, Australia; Department of Psychiatry, Melbourne Medical School, The University of Melbourne, Melbourne, Victoria 3010, Australia; Department of Psychiatry, University of Münster, Münster, Germany.

出版信息

Psychiatry Res. 2019 Apr;274:195-212. doi: 10.1016/j.psychres.2019.02.035. Epub 2019 Feb 18.

DOI:10.1016/j.psychres.2019.02.035
PMID:30807971
Abstract

Social cognition is the ability to identify, perceive and interpret socially relevant information from the external world. It is an important adaptive trait, but is frequently affected in major depressive disorder by a mood-congruent interpretive bias. The present review examined the existing body of literature to determine (i) the impact social cognitive deficits in depression have on psychosocial functioning; and (ii) the utility of psychotropic, psychological and procedural interventions employed to target these deficits. A total of 107 studies met inclusion criteria for review. Social cognitive performance was found to adversely impact depressed patients' psychosocial functioning across the key domains of general cognitive functioning and quality of life. Secondly, many current therapies were found to have a normalising effect on the social cognitive abilities of subjects with major depressive disorder, both at a neural and functional level. In particular, certain anti-depressant medications corrected facial affect recognition deficits, while several psychotherapeutic approaches improved impairments in theory of mind and negative interpretive bias.

摘要

社会认知是指从外部世界识别、感知和解释与社会相关信息的能力。它是一种重要的适应特质,但在重度抑郁症中,常常受到情绪一致的解释偏差的影响。本综述检查了现有文献,以确定 (i) 抑郁患者的社会认知缺陷对心理社会功能的影响;以及 (ii) 用于针对这些缺陷的精神药物、心理和程序干预的有效性。共有 107 项研究符合综述标准。社会认知表现被发现对抑郁症患者的心理社会功能产生负面影响,涉及一般认知功能和生活质量的关键领域。其次,许多当前的治疗方法被发现对重度抑郁症患者的社会认知能力具有正常化作用,无论是在神经和功能层面。特别是,某些抗抑郁药物纠正了面部情感识别缺陷,而几种心理治疗方法则改善了心理理论和负面解释偏差的损伤。

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