Di Mattia Diana, De Bellis Filippo
Praxis Veterinary Clinic, Avellino, Italy.
Vets Now Referrals, Swindon, United Kingdom.
Top Companion Anim Med. 2019 Mar;34:33-35. doi: 10.1053/j.tcam.2018.12.004. Epub 2018 Dec 20.
The coexistence of Leishmania and neoplasia is rarely reported in humans or animals. An 11-year-old intact male mixed-breed dog was presented with a well-demarcated perianal nodule. Cytologic and histopathologic examinations were consistent with the diagnosis of perianal gland adenoma with the presence of Leishmania amastigotes. The dog was considered to be in leishmaniasis stage C (clinically diseased) based on clinical signs, laboratory findings, and serological status. A novel finding in this case report was the presence of Leishmania within the perianal adenoma, probably resulting from an atypical dissemination of the parasites.
利什曼原虫与肿瘤并存的情况在人类或动物中鲜有报道。一只11岁未绝育的雄性混种犬出现了一个边界清晰的肛周结节。细胞学和组织病理学检查结果与肛周腺腺瘤的诊断相符,同时发现了利什曼原虫无鞭毛体。根据临床症状、实验室检查结果和血清学状态,这只狗被认为处于利什曼病C期(临床发病)。本病例报告中的一个新发现是肛周腺瘤内存在利什曼原虫,这可能是由于寄生虫的非典型播散所致。