Broken hearts: Iron overload, ferroptosis and cardiomyopathy.
作者信息
Conrad Marcus, Proneth Bettina
机构信息
Helmholtz Zentrum München, Institute of Developmental Genetics, Ingolstädter Landstr. 1, 85764, Neuherberg, Germany.
出版信息
Cell Res. 2019 Apr;29(4):263-264. doi: 10.1038/s41422-019-0150-y.
Abstract
摘要
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A Dual Role of Heme Oxygenase-1 in Cancer Cells.血红素加氧酶-1 在癌细胞中的双重作用。
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Role of Mitochondria in Ferroptosis.线粒体在铁死亡中的作用。
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Ferroptosis and necroinflammation, a yet poorly explored link.铁死亡与坏死性炎症：一个尚待深入探索的关联。
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TWEAK and RIPK1 mediate a second wave of cell death during AKI.TWEAK 和 RIPK1 在 AKI 期间介导第二波细胞死亡。
Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):4182-4187. doi: 10.1073/pnas.1716578115. Epub 2018 Mar 27.
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Determination of the Subcellular Localization and Mechanism of Action of Ferrostatins in Suppressing Ferroptosis.铁抑素抑制铁死亡的亚细胞定位和作用机制的确定。
ACS Chem Biol. 2018 Apr 20;13(4):1013-1020. doi: 10.1021/acschembio.8b00199. Epub 2018 Mar 13.
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Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease.铁死亡：连接代谢、氧化还原生物学与疾病的一种调控性细胞死亡关联
Cell. 2017 Oct 5;171(2):273-285. doi: 10.1016/j.cell.2017.09.021.
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Regulated necrosis: disease relevance and therapeutic opportunities.程序性坏死：疾病相关性及治疗机遇
Nat Rev Drug Discov. 2016 May;15(5):348-66. doi: 10.1038/nrd.2015.6. Epub 2016 Jan 18.
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Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice.铁死亡调控因子 Gpx4 的失活会引发小鼠急性肾衰竭。
Nat Cell Biol. 2014 Dec;16(12):1180-91. doi: 10.1038/ncb3064. Epub 2014 Nov 17.
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Synchronized renal tubular cell death involves ferroptosis.同步性肾小管细胞死亡涉及铁死亡。
Proc Natl Acad Sci U S A. 2014 Nov 25;111(47):16836-41. doi: 10.1073/pnas.1415518111. Epub 2014 Nov 10.
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Ferroptosis: an iron-dependent form of nonapoptotic cell death.铁死亡：一种依赖于铁的非细胞凋亡性细胞死亡形式。
Cell. 2012 May 25;149(5):1060-72. doi: 10.1016/j.cell.2012.03.042.
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