Song Hyun-Seo, Jung Won-Mo, Lee Ye-Seul, Yoo Seung-Woo, Chae Younbyoung
Acupuncture and Meridian Science Research Center, College of Korean Medicine, Kyung Hee University, Seoul, South Korea.
Department of Anatomy and Acupoint, College of Korean Medicine, Gachon University, Seongnam, South Korea.
Front Neurosci. 2019 Feb 12;13:74. doi: 10.3389/fnins.2019.00074. eCollection 2019.
Humans interpret sensory inputs based on actual stimuli and expectations of the stimuli. We investigated whether manipulating information related to the physiological response could change the somatosensory experience of acupuncture. Twenty-four participants received tactile stimulations with a von Frey filament on the left arm. Participants were informed that they would receive acupuncture stimulations at different angles while they were presented with changes in their peripheral blood flow (PBF) measured with Laser Doppler perfusion imaging. However, in reality, they were observing premade pseudo-biosignal images (six sessions: one circular, two rectangular elongated, two diagonally elongated, and one cross-fixation [control] shape). After each session, the participants reported the intensity and location of the sensations perceived on their arm using a bodily sensation mapping tool. The spatial patterns of the somatic sensations were visualized using statistical parametric mapping. The F1 score was calculated to measure the similarity between the presented pseudo-biosignals and reported response images. The spatial configurations of the presented pseudo-biosignal images and response images were similar. The rectangular elongated pseudo-biosignal shape had a significantly higher F1 score compared to the control. All tactile stimulations produced similar levels of enhanced PBF regardless of the pseudo-biosignal shape. The spatial configurations of somatic sensations changed according to the presented pseudo-biosignal shape, suggesting that expectations of the physiological response to acupuncture stimulation can influence the perceived somatic sensation.
人类根据实际刺激和对刺激的预期来解释感官输入。我们研究了操纵与生理反应相关的信息是否会改变针刺的体感体验。24名参与者的左臂接受了用von Frey细丝进行的触觉刺激。参与者被告知，在他们看到用激光多普勒灌注成像测量的外周血流（PBF）变化时，他们将接受不同角度的针刺刺激。然而，实际上，他们正在观察预先制作的伪生物信号图像（六个阶段：一个圆形、两个长方形拉长形、两个对角拉长形和一个十字固定[对照]形状）。每个阶段后，参与者使用身体感觉映射工具报告他们在手臂上感知到的感觉的强度和位置。使用统计参数映射将体感的空间模式可视化。计算F1分数以测量呈现的伪生物信号与报告的反应图像之间的相似性。呈现的伪生物信号图像和反应图像的空间配置相似。与对照相比，长方形拉长的伪生物信号形状的F1分数显著更高。无论伪生物信号形状如何，所有触觉刺激都产生了相似程度的PBF增强。体感的空间配置根据呈现的伪生物信号形状而变化，这表明对针刺刺激生理反应的预期可以影响感知到的体感。
